Role of bioactive components of ginger andgarlic in the reduction of Vibrio cholera induced infection in model systems

Cholera is an acute secretory diarrhoea caused by the Gram-negative bacterium Vibrio cholerae (Sack, Sack et al. 2004). In its severe form, cholera gravis, the clinical disease is characterized by the passage of voluminous stools of rice water character that rapidly lead to dehydration. Hypovolemic shock, acidosis, and death can ensue in adults, as well as in children, if prompt and appropriate treatment is not initiated. Two distinctive epidemiologic features of cholera are its tendency to appear in explosive outbreaks, often starting in several distinct foci simultaneously, and its propensity to cause true pandemics that progressively affect many countries in multiple continents over the course of many year