The karyotypes of the HNSCC tumours are complex often near triploid and are composed of multiple numerical and structural abnormalities of the chromosomes3 . Cytogenetic studies have identified deletions in several chromosomal arms e.g., 3p, 4p, 8p21-pter, 9p13-p23, 18q22-qter etc., and also centromeric breakage in several chromosomes necessary for HNSCC development4. Allelotyping studies (using microsatellite markers) of HNSCC have identified >25 per cent LOH in several chromosomal regions e.g., 3p, 4q, 6p, 8p, 9p, 11q etc.5,6 . Among these regions, the deletions in 4q, 6p, 8p/q are proposed to be associated with the development of invasive HNSCC tumours5. The deletion mapping of HNSCC tumours by different investigators have ...
Comparative genomic hybridization (CGH) was used to identify chromosomal imbalances in 19 samples of...
Oral squamous cell carcinoma (SCC) is believed to progress through sequential stages of premalignan...
We investigated how somatic changes in HNSCC interact with environmental and host risk factors and w...
Background & Objectives: Deletions in chromosome 8 (chr.8) have been shown to be necessary for t...
Deletions in chromosome (chr.) 13q occur frequently in head and neck squamous cell carcinoma (HNSCC...
In the deletion mapping of chromosome (chr) 9 in head and neck lesions of the Indian patient populat...
Deletions in chromosome (chr.) 13q occur frequently in head and neck squamous cell carcinoma (HNSCC)...
Head and neck squamous cell carcinoma (HNSCC) is a diverse group of cancers that are frequently aggr...
Cytogenetic analysis was performed on primary tumors, and paired recurrent or metastatic lesions, in...
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common human cancer in all parts of...
Intrinsic genomic instability of an incipient tumor cell drives the development of cancer. In colore...
The candidate tumor suppressor genes’ (TSG) loci on human chromosome 3 (chr.3) were mapped in six dy...
Genomic alteration in head and neck squamous cell carcinoma (HNSCC) was studied in two cell line pai...
Background: Genetic instability of chromosome 11 is a frequent event in many solid tumours, includin...
Contains fulltext : 172579.pdf (publisher's version ) (Closed access)The knowledge...
Comparative genomic hybridization (CGH) was used to identify chromosomal imbalances in 19 samples of...
Oral squamous cell carcinoma (SCC) is believed to progress through sequential stages of premalignan...
We investigated how somatic changes in HNSCC interact with environmental and host risk factors and w...
Background & Objectives: Deletions in chromosome 8 (chr.8) have been shown to be necessary for t...
Deletions in chromosome (chr.) 13q occur frequently in head and neck squamous cell carcinoma (HNSCC...
In the deletion mapping of chromosome (chr) 9 in head and neck lesions of the Indian patient populat...
Deletions in chromosome (chr.) 13q occur frequently in head and neck squamous cell carcinoma (HNSCC)...
Head and neck squamous cell carcinoma (HNSCC) is a diverse group of cancers that are frequently aggr...
Cytogenetic analysis was performed on primary tumors, and paired recurrent or metastatic lesions, in...
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common human cancer in all parts of...
Intrinsic genomic instability of an incipient tumor cell drives the development of cancer. In colore...
The candidate tumor suppressor genes’ (TSG) loci on human chromosome 3 (chr.3) were mapped in six dy...
Genomic alteration in head and neck squamous cell carcinoma (HNSCC) was studied in two cell line pai...
Background: Genetic instability of chromosome 11 is a frequent event in many solid tumours, includin...
Contains fulltext : 172579.pdf (publisher's version ) (Closed access)The knowledge...
Comparative genomic hybridization (CGH) was used to identify chromosomal imbalances in 19 samples of...
Oral squamous cell carcinoma (SCC) is believed to progress through sequential stages of premalignan...
We investigated how somatic changes in HNSCC interact with environmental and host risk factors and w...