Morphological and functional heterogeneity of the splenic macrophage (Mf) population was studied in Leishmania donovani (LD) infected BALB/c mice. On a discontinuous percoll gradient two distinct Mf populations were separated. They differed significantly in size as evident from Scanning Electron Microscopy (SEM). Morphologically, the bigger Mf (LM) showed surface projections, whereas the smaller Mf (SM) was round. As regards the antigen-presenting abilities, the LM of infected animals showed defective antigen-presenting abilities at a later stage of the disease, i.e. 6 months post infection (6I-LM) but not earlier, whereas the SM population remained functionally intact throughout the course of the infection. Further, the 6I-LM showed...
Cutaneous leishmaniasis (CL) is the most common form of leishmaniasis and is caused by several speci...
Leishmania are protozoan parasites which invade mammalian macrophages and multiply as amastigotes in...
Many infectious diseases are associated with parasite persistence, often restricted to certain tissu...
Morphological and functional heterogeneity of the splenic macrophage (Mφ) population was studied in ...
Leishmania donovani-infected splenic macrophages and P388D1 (P388D1(I)) failed to activate T cells i...
Leishmania donovani-infected splenic macrophages and P388D1 (P388D1(I)) failed to activate T cells i...
The evolution of cells of the monocyte-macropbage lineage (MML cells) in the spleen of Leishmania do...
In this study, we compare and contrast various parameters of infection between Balb/c and C57BL/6 mi...
Background: Visceral leishmaniasis (VL) is caused by Leishmania infantum or L. donovani infection. O...
<div><p>Macrophages are specialized antigen-presenting cells that process and present self-antigens ...
The most important immunopathological consequence of infection with Leishmania seen in murine and hu...
Cells belonging to the monocyte-macrophage lineage are known to be among the most important effector...
Macrophages are specialized antigen-presenting cells that process and present self-antigens for indu...
Experimental murine infection with the parasites that cause human visceral leishmaniasis (VL) result...
Leishmania is a trypanosomatid protozoan that is responsible for the disease leishmaniasis. Promasti...
Cutaneous leishmaniasis (CL) is the most common form of leishmaniasis and is caused by several speci...
Leishmania are protozoan parasites which invade mammalian macrophages and multiply as amastigotes in...
Many infectious diseases are associated with parasite persistence, often restricted to certain tissu...
Morphological and functional heterogeneity of the splenic macrophage (Mφ) population was studied in ...
Leishmania donovani-infected splenic macrophages and P388D1 (P388D1(I)) failed to activate T cells i...
Leishmania donovani-infected splenic macrophages and P388D1 (P388D1(I)) failed to activate T cells i...
The evolution of cells of the monocyte-macropbage lineage (MML cells) in the spleen of Leishmania do...
In this study, we compare and contrast various parameters of infection between Balb/c and C57BL/6 mi...
Background: Visceral leishmaniasis (VL) is caused by Leishmania infantum or L. donovani infection. O...
<div><p>Macrophages are specialized antigen-presenting cells that process and present self-antigens ...
The most important immunopathological consequence of infection with Leishmania seen in murine and hu...
Cells belonging to the monocyte-macrophage lineage are known to be among the most important effector...
Macrophages are specialized antigen-presenting cells that process and present self-antigens for indu...
Experimental murine infection with the parasites that cause human visceral leishmaniasis (VL) result...
Leishmania is a trypanosomatid protozoan that is responsible for the disease leishmaniasis. Promasti...
Cutaneous leishmaniasis (CL) is the most common form of leishmaniasis and is caused by several speci...
Leishmania are protozoan parasites which invade mammalian macrophages and multiply as amastigotes in...
Many infectious diseases are associated with parasite persistence, often restricted to certain tissu...