The present invention provides methods of increasing muscle mass and muscle miochodrial oxidative metabolism. Additionally, the invention provides treating various disorders associated with mitochondrial dysfunction, including but not limited to metabolic disorders, muscular dystrophy disorders, neurodegenerative diseases, chronic inflammatory diseases, and diseases of aging
Mitochondria are the organelles that generate energy for the cells and act as biosynthetic and bioen...
AbstractBioenergetic sufficiency can be quantitatively assayed by nuclear magnetic resonance spectro...
Mammalian target of rapamycin complex 1 (mTORC1) is central to the control of cell, organ, and body ...
SummaryTranscriptional coregulators control the activity of many transcription factors and are thoug...
peer reviewedTranscriptional coregulators control the activity of many transcription factors and are...
Skeletal muscle exhibits a high plasticity and accordingly can quickly adapt to different physiologi...
Mitochondrial myopathy (MM) is characterised by muscle weakness, exercise intolerance and various hi...
SummaryNeuromuscular disorders with defects in the mitochondrial ATP-generating system affect a larg...
Neuromuscular diseases (NMDs) are dysfunctions that involve skeletal muscle and cause incorrect comm...
The ability to respond to fluctuations of reactive oxygen species (ROS) within the cell is a central...
Full list of author information is available at the end of the articlevironmental changes [1]. Energ...
Patients with mitochondrial myopathies characteristically exhibit pronounced exercise intolerance, o...
A capacidade de sincronizar vias metabólicas a estímulos ambientais é um aspecto central da homeosta...
Nitric oxide (NO) has been implicated in several cellular processes as a signaling molecule and also...
Thispaper reviews the currentunderstandingof themolecularbasis of theperoxisomeproliferator-activate...
Mitochondria are the organelles that generate energy for the cells and act as biosynthetic and bioen...
AbstractBioenergetic sufficiency can be quantitatively assayed by nuclear magnetic resonance spectro...
Mammalian target of rapamycin complex 1 (mTORC1) is central to the control of cell, organ, and body ...
SummaryTranscriptional coregulators control the activity of many transcription factors and are thoug...
peer reviewedTranscriptional coregulators control the activity of many transcription factors and are...
Skeletal muscle exhibits a high plasticity and accordingly can quickly adapt to different physiologi...
Mitochondrial myopathy (MM) is characterised by muscle weakness, exercise intolerance and various hi...
SummaryNeuromuscular disorders with defects in the mitochondrial ATP-generating system affect a larg...
Neuromuscular diseases (NMDs) are dysfunctions that involve skeletal muscle and cause incorrect comm...
The ability to respond to fluctuations of reactive oxygen species (ROS) within the cell is a central...
Full list of author information is available at the end of the articlevironmental changes [1]. Energ...
Patients with mitochondrial myopathies characteristically exhibit pronounced exercise intolerance, o...
A capacidade de sincronizar vias metabólicas a estímulos ambientais é um aspecto central da homeosta...
Nitric oxide (NO) has been implicated in several cellular processes as a signaling molecule and also...
Thispaper reviews the currentunderstandingof themolecularbasis of theperoxisomeproliferator-activate...
Mitochondria are the organelles that generate energy for the cells and act as biosynthetic and bioen...
AbstractBioenergetic sufficiency can be quantitatively assayed by nuclear magnetic resonance spectro...
Mammalian target of rapamycin complex 1 (mTORC1) is central to the control of cell, organ, and body ...