Autofluorescence detection of tumors in the human lung: comparison between in-vivo and in vitro measurements

To detect bronchial carcinoma by autofluorescence, we measured in-vivo, in an in-vivo model, and in-vitro the spectra of tumor and normal tissue by a fiber-optic-spectrometer. The main difference between tumor and bronchial tissue is the intensity of the 505 nm main peak. © 2005 SPIE-OSA