A phospho-directed nanoreactor with multiple functions is reported. Alumina-functionalized macroporous ordered silica foams (Al-MOSF) have been developed with large pore size, high pore volume (1.6 cm(3)/g), and a surface area of 186 m(2)/g rich in coordination unsaturated Al species, which can be used as phospho-directed nanoreactors for integrated in situ digestion and in situ phosphoisolation. By directly adding Al-MOSF to the conventional in-solution digestion system, both enzymes and proteins are quickly enriched in the macropores of the reactor to achieve a fast proteolysis without increasing the enzyme/protein concentration or using a preimmobilization process, thus the digestion time and the cost can be greatly reduced. Meanwhile, d...
Multiamines with amphiphilic structures have been synthesized to serve as simultaneous structure-dir...
An integrated protocol is proposed here for efficient analysis of membrane proteins based on surface...
In eukaryotic cells, enzymes are compartmentalized into specific organelles so that different reacti...
A phospho-directed nanoreactor with multiple functions is reported. Alumina-functionalized macroporo...
We have developed a smart nanodevice for the highly efficient and selective detection of glycoprotei...
Alumina has recently turned out to be effective in enrichment of biomacrolecules like phosphopeptide...
A novel nanopore based digestion strategy has been developed by directly adding a macroporous materi...
Nanoporous alumina is a rather newly characterized material that so far has found limited use in the...
AbstractSilica monoliths with hierarchical porosity (macro-/mesoporous), prepared by a combination o...
A versatile protocol has been developed for large-scale characterization of hydrophobic membrane pro...
Because of its good biocompatibility, high surface-to-volume ratio, and distinct surface electrical ...
The conventional protocols for in solution or in gel protein digestion require many steps and long r...
Mesoporous materials are very attractive solids for the fabrication of confined nanoreactors since t...
Mesoporous silica materials are versatile platforms for biological catalysis, isolation of small mol...
Fabrication and photophysical study of photofunctional nanoporous alumina membrane (PNAM) were perfo...
Multiamines with amphiphilic structures have been synthesized to serve as simultaneous structure-dir...
An integrated protocol is proposed here for efficient analysis of membrane proteins based on surface...
In eukaryotic cells, enzymes are compartmentalized into specific organelles so that different reacti...
A phospho-directed nanoreactor with multiple functions is reported. Alumina-functionalized macroporo...
We have developed a smart nanodevice for the highly efficient and selective detection of glycoprotei...
Alumina has recently turned out to be effective in enrichment of biomacrolecules like phosphopeptide...
A novel nanopore based digestion strategy has been developed by directly adding a macroporous materi...
Nanoporous alumina is a rather newly characterized material that so far has found limited use in the...
AbstractSilica monoliths with hierarchical porosity (macro-/mesoporous), prepared by a combination o...
A versatile protocol has been developed for large-scale characterization of hydrophobic membrane pro...
Because of its good biocompatibility, high surface-to-volume ratio, and distinct surface electrical ...
The conventional protocols for in solution or in gel protein digestion require many steps and long r...
Mesoporous materials are very attractive solids for the fabrication of confined nanoreactors since t...
Mesoporous silica materials are versatile platforms for biological catalysis, isolation of small mol...
Fabrication and photophysical study of photofunctional nanoporous alumina membrane (PNAM) were perfo...
Multiamines with amphiphilic structures have been synthesized to serve as simultaneous structure-dir...
An integrated protocol is proposed here for efficient analysis of membrane proteins based on surface...
In eukaryotic cells, enzymes are compartmentalized into specific organelles so that different reacti...