The process of multi-objective optimization involves finding optimal solutions to several objective functions. However, these are typically in conflict with each other in many real-world problems, such as production system design. Advanced post-optimization analysis can be used to provide the decision maker with information about the underlying system. The analysis can be based on the combination of simulation-based multi-objective optimization and learning from the obtained solution set. The goal of the analysis is to gain a deeper understanding of the problem at hand, to systematically explore and evaluate different alternatives, and to generate essential information and knowledge to support the decision maker to make more informed decisi...