In this paper, the philosophy of a research in pharmacology field, driven by an engineering approach, was described along with some case histories and examples. The improvement in the testing methods for pharmaceutical systems (in-vitro techniques), as well as the proposal and the testing of mathematical models to describe the pharmacokinetics (in-silico techniques) are reported with the aim of pointing out methodologies and tools able to reduce the need of expensive and ethical problematic in-vivo measurements
Amongst the entire potential spectrum of expansion of the engineering sciences as an omnipresent fie...
Introduction: The assessment of intestinal membrane permeability properties of new chemical entities...
The recent advent of microphysiological systems-microfluidic biomimetic devices that aspire to emula...
In this paper, the philosophy of a research in pharmacology field, driven by an engineering approach...
In this work an engineering approach, consisting in an experimental procedure and a model to deriv...
Introduction: The pharmacokinetic properties of anti-infective drugs are a determinant part of treat...
To predict the drug hemeatic levels after administration is a goal of great interest in the design o...
The pharmaceutical industry seeks to more efficient and precise determination of the main pharmacoki...
Modeling and simulation in pharmacokinetics has has turned into the focus of pharmaceutical companie...
After its oral administration, a pharmaceutical form is subjected to several factors potentially inf...
Pharmacokinetic studies have turned into the focus of pharmaceutical companies, after studies manife...
Costs, scientific and ethical concerns related to animal tests for regulatory decision-making have s...
Pharmaceutical industry and regulatory agencies consider mathematical modeling as a valuable tool to...
Amongst the entire potential spectrum of expansion of the engineering sciences as an omnipresent fie...
Introduction: The assessment of intestinal membrane permeability properties of new chemical entities...
The recent advent of microphysiological systems-microfluidic biomimetic devices that aspire to emula...
In this paper, the philosophy of a research in pharmacology field, driven by an engineering approach...
In this work an engineering approach, consisting in an experimental procedure and a model to deriv...
Introduction: The pharmacokinetic properties of anti-infective drugs are a determinant part of treat...
To predict the drug hemeatic levels after administration is a goal of great interest in the design o...
The pharmaceutical industry seeks to more efficient and precise determination of the main pharmacoki...
Modeling and simulation in pharmacokinetics has has turned into the focus of pharmaceutical companie...
After its oral administration, a pharmaceutical form is subjected to several factors potentially inf...
Pharmacokinetic studies have turned into the focus of pharmaceutical companies, after studies manife...
Costs, scientific and ethical concerns related to animal tests for regulatory decision-making have s...
Pharmaceutical industry and regulatory agencies consider mathematical modeling as a valuable tool to...
Amongst the entire potential spectrum of expansion of the engineering sciences as an omnipresent fie...
Introduction: The assessment of intestinal membrane permeability properties of new chemical entities...
The recent advent of microphysiological systems-microfluidic biomimetic devices that aspire to emula...