Measured adiposity in relation to head and neck cancer risk in the European prospective investigation into cancer and nutrition.
- Ward, Heather A.
- Wark, Petra A.
- Muller, David C.
- Steffen, Annika
- Johansson, Mattias
- Norat, Teresa
- Gunter, Marc J.
- Overvad, Kim
- Dahm, Christina C
- Halkjær, Jytte
- Tjønneland, Anne
- Boutron-Ruault, Marie-Christine
- Fagherazzi, Guy
- Mesrine, Sylvie
- Brennan, Paul
- Freisling, Heinz
- Li, Kuanrong
- Kaaks, Rudolf
- Trichopoulou, Antonia
- Lagiou, Pagona
- Panico, Salavatore
- Grioni, Sara
- Tumino, Rosario
- Vineis, Paolo
- Palli, Domenico
- Peeters, Petra H.M.
- Bueno-De-Mesquita, Hendrik Bastiaan
- Weiderpass, Elisabete
- Agudo, Antonio
- Quirós, José Ramón
- Larrañaga, Nerea
- Ardanaz, Eva
- Huerta, José María
- Sánchez, María-José
- Laurell, Göran
- Johansson, Ingegerd
- Westin, Ulla
- Wallström, Peter
- Bradbury, Kathryn E.
- Wareham, Nicholas J.
- Khaw, Kay-Tee
- Pearson, Clare
- Boeing, Heiner
- Riboli, Elio
DOIAbstract
Background: Emerging evidence from cohort studies indicates that adiposity is associated with greater incidence of head and neck cancer. However, most studies have used self-reported anthropometry which is prone to error.Methods: Among 363,094 participants in the European Prospective Investigation into Cancer and Nutrition study (EPIC) with measured anthropometry, there were 837 incident cases of head and neck cancer. Head and neck cancer risk was examined in relation to body mass index (BMI) [lean: Results: Among men, a BMI Conclusions: Central adiposity, particularly among women, may have a stronger association with head and neck cancer risk than previously estimated.Impact: Strategies to reduce obesity may beneficially impact head and ne...
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