Add to ORKGPhosphatase and tensin homolog (PTEN) belong to the group of gatekeepers tumour suppressor genes and is involved in multiple mechanisms leading to cellular defense against neoplastic transformation and progression. Twenty four dogs and 17 cats were submitted to a two-years follow-up and clinico-pathological features were recorded and compared with immunohistochemical PTEN expression. PTEN-negative status occurred in 33% of canine and 76% of feline mammary carcinomas. In canine mammary carcinomas there was a significant (P<0.05) correlation among PTEN loss of protein expression and simple carcinoma histotype, presence of lymphatic invasion, lymph-node metastases, distant organ metastases, tumour dedifferentiation, tumour recurrence, and shor...
International audienceFeline invasive mammary carcinomas are characterized by their high clinical ag...
Copy number aberrations frequently occur during the development of many cancers. Such events affect ...
<div><p>Background</p><p>Copy number aberrations frequently occur during the development of many can...
Phosphatase and tensin homolog deleted on chromosome10 (PTEN), phospho-v-Akt murine thymoma viral on...
AN IMMUNOHISTOCHEMICAL STUDY OF THE PTEN/AKT PATHWAY INVOLVEMENT IN CANINE AND FELINE MAMMARY TUMOUR...
Fifty-four canine mammary lesions (15 hyperplasias, 7 adenomas and 32 carcinomas) were submitted to ...
lntroduction: PTEN is a tumor suppressor protein that negatively regulates tumor growth and invasive...
The PTEN/AKT pathway plays a key role in several biological effects such as cell metabolism, cell pr...
Phosphatase and tensin homolog deleted on chromosome10 (PTEN), phospho-v-Akt murine thymoma viral on...
Signal transducer and activator of transcription 3 (STAT3) and phosphatase and tensin homologue (PTE...
Abstract. Canine osteosarcoma (OS) cell lines contain mutations that directly or indirectly inactiva...
Most feline mammary tumours are aggressive carcinomas (80-90%) with poor prognosis. When compared to...
Abstract. We examined the presence of phosphatase and tensin homolog deleted from chromosome 10 (PTE...
Background Copy number aberrations frequently occur during the development of many cancers. Such eve...
E-cadherin and \u3b2-catenin have been studied in carcinogenesis and tumour progression and reduced ...
International audienceFeline invasive mammary carcinomas are characterized by their high clinical ag...
Copy number aberrations frequently occur during the development of many cancers. Such events affect ...
<div><p>Background</p><p>Copy number aberrations frequently occur during the development of many can...
Phosphatase and tensin homolog deleted on chromosome10 (PTEN), phospho-v-Akt murine thymoma viral on...
AN IMMUNOHISTOCHEMICAL STUDY OF THE PTEN/AKT PATHWAY INVOLVEMENT IN CANINE AND FELINE MAMMARY TUMOUR...
Fifty-four canine mammary lesions (15 hyperplasias, 7 adenomas and 32 carcinomas) were submitted to ...
lntroduction: PTEN is a tumor suppressor protein that negatively regulates tumor growth and invasive...
The PTEN/AKT pathway plays a key role in several biological effects such as cell metabolism, cell pr...
Phosphatase and tensin homolog deleted on chromosome10 (PTEN), phospho-v-Akt murine thymoma viral on...
Signal transducer and activator of transcription 3 (STAT3) and phosphatase and tensin homologue (PTE...
Abstract. Canine osteosarcoma (OS) cell lines contain mutations that directly or indirectly inactiva...
Most feline mammary tumours are aggressive carcinomas (80-90%) with poor prognosis. When compared to...
Abstract. We examined the presence of phosphatase and tensin homolog deleted from chromosome 10 (PTE...
Background Copy number aberrations frequently occur during the development of many cancers. Such eve...
E-cadherin and \u3b2-catenin have been studied in carcinogenesis and tumour progression and reduced ...
International audienceFeline invasive mammary carcinomas are characterized by their high clinical ag...
Copy number aberrations frequently occur during the development of many cancers. Such events affect ...
<div><p>Background</p><p>Copy number aberrations frequently occur during the development of many can...