Tissue engineering of a morphologically and functionally intact humanized bone organ for bone metastasis research | ORKG Ask

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Engineering a humanized bone organ model in mice to study bone metastases

Martine, L.C.
Holzapfel, B.M.
McGovern, J.A.
Wagner, F.
Quent, V.M.
Hesami, P.
Wunner, F.M.
Vaquette, C.
De-Juan-Pardo, E.M.
Brown, T.D.
Nowlan, B.
Wu, D.J.
Hutmacher, C.O.
Moi, D.
Oussenko, T.
Piccinini, E.
Zandstra, P.W.
Mazzieri, R.
Lévesque, J.P.
Dalton, P.D.
Taubenberger, A.V.
Hutmacher, D.W.

April 2017

Current in vivo models for investigating human primary bone tumors and cancer metastasis to the bone...

Engineering a humanized bone organ model in mice to study bone metastases

Martine, Laure C.
Holzapfel, Boris M.
McGovern, Jacqui A.
Wagner, Ferdinand
Quent, Verena M.
Hesami, Parisa
Wunner, Felix M.
Vaquette, Cedryck
De-Juan-Pardo, Elena M.
Brown, Toby D.
Nowlan, Bianca
Wu, Dan Jing
Hutmacher, Cosmo Orlando
Moi, Davide
Oussenko, Tatiana
Piccinini, Elia
Zandstra, Peter W.
Mazzieri, Roberta
Lévesque, Jean-Pierre
Dalton, Paul D.
Taubenberger, Anna V.
Hutmacher, Dietmar W.

January 2017

Current in vivo models for investigating human primary bone tumors and cancer metastasis to the bone...

Engineering a humanized bone organ model in mice to study bone metastases

Martine, Laure C.
Holzapfel, Boris M.
McGovern, Jacqui A.
Wagner, Ferdinand
Quent, Verena M.
Hesami, Parisa
Wunner, Felix M.
Vaquette, Cedryck
De-Juan-Pardo, Elena M.
Brown, Toby D.
Nowlan, Bianca
Wu, Dan Jing
Hutmacher, Cosmo Orlando
Moi, Davide
Oussenko, Tatiana
Piccinini, Elia
Zandstra, Peter W.
Mazzieri, Roberta
Levesque, Jean-Pierre
Dalton, Paul D.
Taubenberger, Anna V.
Hutmacher, Dietmar W.

April 2017

Current in vivo models for investigating human primary bone tumors and cancer metastasis to the bone...

Engineering a humanized bone organ model in mice to study bone metastases

Martine, L.C.
Holzapfel, B.M.
McGovern, J.A.
Wagner, F.
Quent, V.M.
Hesami, P.
Wunner, F.M.
Vaquette, C.
De-Juan-Pardo, E.M.
Brown, T.D.
Nowlan, B.
Wu, D.J.
Hutmacher, C.O.
Moi, D.
Oussenko, T.
Piccinini, E.
Zandstra, P.W.
Mazzieri, R.
Lévesque, J.P.
Dalton, P.D.
Taubenberger, A.V.
Hutmacher, D.W.

April 2017

Current in vivo models for investigating human primary bone tumors and cancer metastasis to the bone...

Engineering a humanized bone organ model in mice to study bone metastases

Martine, L.C.
Holzapfel, B.M.
McGovern, J.A.
Wagner, F.
Quent, V.M.
Hesami, P.
Wunner, F.M.
Vaquette, C.
De-Juan-Pardo, E.M.
Brown, T.D.
Nowlan, B.
Wu, D.J.
Hutmacher, C.O.
Moi, D.
Oussenko, T.
Piccinini, E.
Zandstra, P.W.
Mazzieri, R.
Lévesque, J.P.
Dalton, P.D.
Taubenberger, A.V.
Hutmacher, D.W.

April 2017

Current in vivo models for investigating human primary bone tumors and cancer metastasis to the bone...

Engineering a humanized bone organ model in mice to study bone metastases

Martine, L.C.
Holzapfel, B.M.
McGovern, J.A.
Wagner, F.
Quent, V.M.
Hesami, P.
Wunner, F.M.
Vaquette, C.
De-Juan-Pardo, E.M.
Brown, T.D.
Nowlan, B.
Wu, D.J.
Hutmacher, C.O.
Moi, D.
Oussenko, T.
Piccinini, E.
Zandstra, P.W.
Mazzieri, R.
Lévesque, J.P.
Dalton, P.D.
Taubenberger, A.V.
Hutmacher, D.W.

April 2017

Current in vivo models for investigating human primary bone tumors and cancer metastasis to the bone...

Engineering a humanized bone organ model in mice to study bone metastases

Martine, L.C.
Holzapfel, B.M.
McGovern, J.A.
Wagner, F.
Quent, V.M.
Hesami, P.
Wunner, F.M.
Vaquette, C.
De-Juan-Pardo, E.M.
Brown, T.D.
Nowlan, B.
Wu, D.J.
Hutmacher, C.O.
Moi, D.
Oussenko, T.
Piccinini, E.
Zandstra, P.W.
Mazzieri, R.
Lévesque, J.P.
Dalton, P.D.
Taubenberger, A.V.
Hutmacher, D.W.

April 2017

Current in vivo models for investigating human primary bone tumors and cancer metastasis to the bone...

Engineering a humanized bone organ model in mice to study bone metastases

Martine, Laure
Holzapfel, Boris
McGovern, Jacqui
Wagner, Ferdinand
Quent, Verena
Hesami, Parisa
Wunner, Felix
Vaquette, Cedryck
Juan Pardo, Elena
Brown, Toby
Nowlan, Bianca
Wu, Dan Jing
Hutmacher, Cosmo
Moi, Davide
Oussenko, Tatiana
Piccinini, Elia
Zandstra, Peter
Mazzieri, Roberta
Levesque, Jean-Pierre
Dalton, Paul
Taubenberger, Anna
Hutmacher, Dietmar

January 2017

Current in vivo models for investigating human primary bone tumors and cancer metastasis to the bone...

Engineering a humanized bone organ model in mice to study bone metastases

Martine, L.C.
Holzapfel, B.M.
McGovern, J.A.
Wagner, F.
Quent, V.M.
Hesami, P.
Wunner, F.M.
Vaquette, C.
De-Juan-Pardo, E.M.
Brown, T.D.
Nowlan, B.
Wu, D.J.
Hutmacher, C.O.
Moi, D.
Oussenko, T.
Piccinini, E.
Zandstra, P.W.
Mazzieri, R.
Levesque, J.-P.
Dalton, P.D.
Taubenberger, A.V.
Hutmacher, D.W.

April 2017

Current in vivo models for investigating human primary bone tumors and cancer metastasis to the bone...

Engineering a humanized bone organ model in mice to study bone metastases

Martine, LC
Holzapfel, BM
McGovern, JA
Wagner, F (Ferdinand)
Quent, Verena M
Hesami, P
Wunner, FM
Vaquette, C
De-Juan-Pardo, EM
Brown, TD
Nowlan, Bianca
Wu, D Dan
Hutmacher, CO
Moi, D
Oussenko, T
Piccinini, Elia
Zandstra, PW
Mazzieri, R
Lévesque, JP
Dalton, PD
Taubenberger, AV
Hutmacher, DW

January 2017

\u3cp\u3eCurrent in vivo models for investigating human primary bone tumors and cancer metastasis to...

Immune system augmentation via humanization using stem/progenitor cells and bioengineering in a breast cancer model study

Shafiee, Abbas
McGovern, Jacqui
Lahr, Christoph Alexander
Meinert, Christoph
Moi, Davide
Wagner, Ferdinand
Landgraf, Marietta
Juan Pardo, Elena
Mazzieri, Roberta
Hutmacher, Dietmar

January 2018

Despite significant advances, most current in vivo models fail to fully recapitulate the biological ...

Engineering a humanized bone organ model in mice to study bone metastases

Martine, L.C.
Holzapfel, B.M.
McGovern, J.A.
Wagner, F.
Quent, V.M.
Hesami, P.
Wunner, F.M.
Vaquette, C.
De-Juan-Pardo, E.M.
Brown, T.D.
Nowlan, B.
Wu, D.J.
Hutmacher, C.O.
Moi, D.
Oussenko, T.
Piccinini, E.
Zandstra, P.W.
Mazzieri, R.
Lévesque, J.P.
Dalton, P.D.
Taubenberger, A.V.
Hutmacher, D.W.

April 2017

Current in vivo models for investigating human primary bone tumors and cancer metastasis to the bone...

Engineering a humanized bone organ model in mice to study bone metastases

Martine, Laure C.
Holzapfel, Boris M.
McGovern, Jacqui A.
Wagner, Ferdinand
Quent, Verena M.
Hesami, Parisa
Wunner, Felix M.
Vaquette, Cedryck
De-Juan-Pardo, Elena M.
Brown, Toby D.
Nowlan, Bianca
Wu, Dan Jing
Hutmacher, Cosmo Orlando
Moi, Davide
Oussenko, Tatiana
Piccinini, Elia
Zandstra, Peter W.
Mazzieri, Roberta
Lévesque, Jean-Pierre
Dalton, Paul D.
Taubenberger, Anna V.
Hutmacher, Dietmar W.

January 2017

Current in vivo models for investigating human primary bone tumors and cancer metastasis to the bone...

Engineering a humanized bone organ model in mice to study bone metastases

Martine, Laure C.
Holzapfel, Boris M.
McGovern, Jacqui A.
Wagner, Ferdinand
Quent, Verena M.
Hesami, Parisa
Wunner, Felix M.
Vaquette, Cedryck
De-Juan-Pardo, Elena M.
Brown, Toby D.
Nowlan, Bianca
Wu, Dan Jing
Hutmacher, Cosmo Orlando
Moi, Davide
Oussenko, Tatiana
Piccinini, Elia
Zandstra, Peter W.
Mazzieri, Roberta
Levesque, Jean-Pierre
Dalton, Paul D.
Taubenberger, Anna V.
Hutmacher, Dietmar W.

April 2017

Current in vivo models for investigating human primary bone tumors and cancer metastasis to the bone...

Engineering a humanized bone organ model in mice to study bone metastases

Martine, L.C.
Holzapfel, B.M.
McGovern, J.A.
Wagner, F.
Quent, V.M.
Hesami, P.
Wunner, F.M.
Vaquette, C.
De-Juan-Pardo, E.M.
Brown, T.D.
Nowlan, B.
Wu, D.J.
Hutmacher, C.O.
Moi, D.
Oussenko, T.
Piccinini, E.
Zandstra, P.W.
Mazzieri, R.
Lévesque, J.P.
Dalton, P.D.
Taubenberger, A.V.
Hutmacher, D.W.

April 2017

Current in vivo models for investigating human primary bone tumors and cancer metastasis to the bone...

Engineering a humanized bone organ model in mice to study bone metastases

Martine, L.C.
Holzapfel, B.M.
McGovern, J.A.
Wagner, F.
Quent, V.M.
Hesami, P.
Wunner, F.M.
Vaquette, C.
De-Juan-Pardo, E.M.
Brown, T.D.
Nowlan, B.
Wu, D.J.
Hutmacher, C.O.
Moi, D.
Oussenko, T.
Piccinini, E.
Zandstra, P.W.
Mazzieri, R.
Lévesque, J.P.
Dalton, P.D.
Taubenberger, A.V.
Hutmacher, D.W.

April 2017

Current in vivo models for investigating human primary bone tumors and cancer metastasis to the bone...

Engineering a humanized bone organ model in mice to study bone metastases

Martine, L.C.
Holzapfel, B.M.
McGovern, J.A.
Wagner, F.
Quent, V.M.
Hesami, P.
Wunner, F.M.
Vaquette, C.
De-Juan-Pardo, E.M.
Brown, T.D.
Nowlan, B.
Wu, D.J.
Hutmacher, C.O.
Moi, D.
Oussenko, T.
Piccinini, E.
Zandstra, P.W.
Mazzieri, R.
Lévesque, J.P.
Dalton, P.D.
Taubenberger, A.V.
Hutmacher, D.W.

April 2017

Current in vivo models for investigating human primary bone tumors and cancer metastasis to the bone...

Engineering a humanized bone organ model in mice to study bone metastases

Martine, L.C.
Holzapfel, B.M.
McGovern, J.A.
Wagner, F.
Quent, V.M.
Hesami, P.
Wunner, F.M.
Vaquette, C.
De-Juan-Pardo, E.M.
Brown, T.D.
Nowlan, B.
Wu, D.J.
Hutmacher, C.O.
Moi, D.
Oussenko, T.
Piccinini, E.
Zandstra, P.W.
Mazzieri, R.
Lévesque, J.P.
Dalton, P.D.
Taubenberger, A.V.
Hutmacher, D.W.

April 2017

Current in vivo models for investigating human primary bone tumors and cancer metastasis to the bone...

Engineering a humanized bone organ model in mice to study bone metastases

Martine, Laure
Holzapfel, Boris
McGovern, Jacqui
Wagner, Ferdinand
Quent, Verena
Hesami, Parisa
Wunner, Felix
Vaquette, Cedryck
Juan Pardo, Elena
Brown, Toby
Nowlan, Bianca
Wu, Dan Jing
Hutmacher, Cosmo
Moi, Davide
Oussenko, Tatiana
Piccinini, Elia
Zandstra, Peter
Mazzieri, Roberta
Levesque, Jean-Pierre
Dalton, Paul
Taubenberger, Anna
Hutmacher, Dietmar

January 2017

Current in vivo models for investigating human primary bone tumors and cancer metastasis to the bone...

Engineering a humanized bone organ model in mice to study bone metastases

Martine, L.C.
Holzapfel, B.M.
McGovern, J.A.
Wagner, F.
Quent, V.M.
Hesami, P.
Wunner, F.M.
Vaquette, C.
De-Juan-Pardo, E.M.
Brown, T.D.
Nowlan, B.
Wu, D.J.
Hutmacher, C.O.
Moi, D.
Oussenko, T.
Piccinini, E.
Zandstra, P.W.
Mazzieri, R.
Levesque, J.-P.
Dalton, P.D.
Taubenberger, A.V.
Hutmacher, D.W.

April 2017

Current in vivo models for investigating human primary bone tumors and cancer metastasis to the bone...

Engineering a humanized bone organ model in mice to study bone metastases

Martine, LC
Holzapfel, BM
McGovern, JA
Wagner, F (Ferdinand)
Quent, Verena M
Hesami, P
Wunner, FM
Vaquette, C
De-Juan-Pardo, EM
Brown, TD
Nowlan, Bianca
Wu, D Dan
Hutmacher, CO
Moi, D
Oussenko, T
Piccinini, Elia
Zandstra, PW
Mazzieri, R
Lévesque, JP
Dalton, PD
Taubenberger, AV
Hutmacher, DW

January 2017

\u3cp\u3eCurrent in vivo models for investigating human primary bone tumors and cancer metastasis to...

Immune system augmentation via humanization using stem/progenitor cells and bioengineering in a breast cancer model study

Shafiee, Abbas
McGovern, Jacqui
Lahr, Christoph Alexander
Meinert, Christoph
Moi, Davide
Wagner, Ferdinand
Landgraf, Marietta
Juan Pardo, Elena
Mazzieri, Roberta
Hutmacher, Dietmar

January 2018

Despite significant advances, most current in vivo models fail to fully recapitulate the biological ...