A major obstacle to 3-dimensional tissue engineering is incorporation of a functional vascular supply to support the expanding new tissue. This is overcome in an in vivo intrinsic vascularization model where an arteriovenous loop (AVL) is placed in a noncollapsible space protected by a polycarbonate chamber. Vascular development and hypoxia were examined from 3 days to 112 days by vascular casting, morphometric, and morphological techniques to understand the model's vascular growth and remodeling parameters for tissue engineering purposes. At 3 days a fibrin exudate surrounded the AVL, providing a scaffold to migrating inflammatory, endothelial, and mesenchymal cells. Capillaries formed between 3 and 7 days. Hypoxia and cell proliferation w...
Tissue engineering and regenerative medicine aim at restoring a damaged tissue by recreating in vitr...
Tissue vascularization and integration with host circulation remains a key barrier to the translatio...
The success of tissue engineering hinges on the rapid and sufficient vascularization of the neotissu...
A major obstacle to 3-dimensional tissue engineering is incorporation of a functional vascular suppl...
In reconstructive surgery, there is a clinical need for an alternative to the current methods of aut...
ObjectivesDense angiogenic sprouting occurs from arteriovenous loops (AVLs) incorporating autologous...
Background: An arteriovenous loop (AVL) enclosed in a polycarbonate chamber in vivo, produces a fibr...
The authors have previously described a model of in vivo tissue generation based on an implanted, mi...
In a recently described model for tissue engineering, an arteriovenous loop comprising the femoral a...
BackgroundAn arteriovenous loop (AVL) enclosed in a polycarbonate chamber in vivo, produces a fibrin...
The authors previously described a model of tissue engineering in rats that involves the insertion o...
One of the greatest challenges currently faced in tissue engineering is the incorporation of vascula...
In tissue engineering, the generation and functional maintenance of dense voluminous tissues is main...
One critical obstacle facing tissue engineering is the formation of functional vascular networks tha...
Proper growth of blood vessels is critical for development, wound healing and homeostasis. This proc...
Tissue engineering and regenerative medicine aim at restoring a damaged tissue by recreating in vitr...
Tissue vascularization and integration with host circulation remains a key barrier to the translatio...
The success of tissue engineering hinges on the rapid and sufficient vascularization of the neotissu...
A major obstacle to 3-dimensional tissue engineering is incorporation of a functional vascular suppl...
In reconstructive surgery, there is a clinical need for an alternative to the current methods of aut...
ObjectivesDense angiogenic sprouting occurs from arteriovenous loops (AVLs) incorporating autologous...
Background: An arteriovenous loop (AVL) enclosed in a polycarbonate chamber in vivo, produces a fibr...
The authors have previously described a model of in vivo tissue generation based on an implanted, mi...
In a recently described model for tissue engineering, an arteriovenous loop comprising the femoral a...
BackgroundAn arteriovenous loop (AVL) enclosed in a polycarbonate chamber in vivo, produces a fibrin...
The authors previously described a model of tissue engineering in rats that involves the insertion o...
One of the greatest challenges currently faced in tissue engineering is the incorporation of vascula...
In tissue engineering, the generation and functional maintenance of dense voluminous tissues is main...
One critical obstacle facing tissue engineering is the formation of functional vascular networks tha...
Proper growth of blood vessels is critical for development, wound healing and homeostasis. This proc...
Tissue engineering and regenerative medicine aim at restoring a damaged tissue by recreating in vitr...
Tissue vascularization and integration with host circulation remains a key barrier to the translatio...
The success of tissue engineering hinges on the rapid and sufficient vascularization of the neotissu...