Add to ORKGThis was a random-order, double blind cross-over trial of 2 formulations of a ready-to-use supplementary food (RUSF), one fortified with arginine and citrulline and provided with a daily anti-inflammatory dose of chloroquine (RUSF-v) and a basic formulation (RUSF-b) provided with a standard anti-malarial prophylactic weekly dose of chloroquine. The study was designed to test the hypotheses: (1) supplementary arginine, citrulline and daily chloroquine increases bioavailable arginine and flow-mediated-dilatation (FMDmax%; a measure of NO-dependent endothelial function), and (2); protein energy supplementation in the form of RUSF improves nutritional status in children with sickle cell disease
Aims: The aim of this study is to assess the efficacy and safety of Drepanoalpha®, a nutraceutical u...
Background. Sickle cell anaemia (SCA) is the most prevalentmonogenic disease in Brazil. In SCA, haem...
BACKGROUND: Sickle cell anaemia (SCA) is an inherited disorder of haemoglobin. Patients experience l...
This protocol outlines procedures for capturing participant information as part of the V-FIT study....
Background: Sickle-cell disease increases the risk of malnutrition. Low arginine and nitric oxide bi...
Introduction: Endothelial function is impaired in sickle cell anemia (SCA) and may be prognostic of ...
BACKGROUND: Despite substantial illness burden and healthcare utilization conferred by pain from vas...
Abstract Background Despite substantial illness burden and healthcare utilization conferred by pain ...
Poor nutritional status is common in SCD but there are no strategies to improve nutrition. Vascular ...
Background: Sickle cell disease (SCD) is endemic in non-Western countries. Due to migration, the pre...
Background. Sickle cell anaemia (SCA) is the most prevalent monogenic disease in Brazil. In SCA, hae...
Background: The orphan status of sickle cell invites many researchers toward drug development in the...
Objectives: Sickle cell disease (SCD), an inherited hemoglobinopathy that causes anemia, severe pain...
The clinical trials seek to investigate the safety of hydroxyurea as a supportive treatment in child...
BACKGROUND: Sickle cell anemia is an inherited blood disorder that is characterized by painful vaso-...
Aims: The aim of this study is to assess the efficacy and safety of Drepanoalpha®, a nutraceutical u...
Background. Sickle cell anaemia (SCA) is the most prevalentmonogenic disease in Brazil. In SCA, haem...
BACKGROUND: Sickle cell anaemia (SCA) is an inherited disorder of haemoglobin. Patients experience l...
This protocol outlines procedures for capturing participant information as part of the V-FIT study....
Background: Sickle-cell disease increases the risk of malnutrition. Low arginine and nitric oxide bi...
Introduction: Endothelial function is impaired in sickle cell anemia (SCA) and may be prognostic of ...
BACKGROUND: Despite substantial illness burden and healthcare utilization conferred by pain from vas...
Abstract Background Despite substantial illness burden and healthcare utilization conferred by pain ...
Poor nutritional status is common in SCD but there are no strategies to improve nutrition. Vascular ...
Background: Sickle cell disease (SCD) is endemic in non-Western countries. Due to migration, the pre...
Background. Sickle cell anaemia (SCA) is the most prevalent monogenic disease in Brazil. In SCA, hae...
Background: The orphan status of sickle cell invites many researchers toward drug development in the...
Objectives: Sickle cell disease (SCD), an inherited hemoglobinopathy that causes anemia, severe pain...
The clinical trials seek to investigate the safety of hydroxyurea as a supportive treatment in child...
BACKGROUND: Sickle cell anemia is an inherited blood disorder that is characterized by painful vaso-...
Aims: The aim of this study is to assess the efficacy and safety of Drepanoalpha®, a nutraceutical u...
Background. Sickle cell anaemia (SCA) is the most prevalentmonogenic disease in Brazil. In SCA, haem...
BACKGROUND: Sickle cell anaemia (SCA) is an inherited disorder of haemoglobin. Patients experience l...