Nanostructures possess distinct quenching ability toward fluorophores with different emission frequencies and have been intensively used as nanoquenchers for homogeneous nucleic acid detection. Complete understanding of such a sensing system will provide significant guidance for the design of superior sensing materials, which is still lacking. In this Letter, we demonstrate the development of FeP nanowires as a nanoquencher for high-performance fluorescent nucleic acid detection with much superior performance to alpha-Fe(2)O3 counterparts. The whole detection process is complete within 1 min, and this fluorosensor presents a detection limit as low as 4 pM with strong discrimination of single-point mutation. Electrochemical tests and density...
We describe a novel application for detecting specific single strand DNA sequences using multisegmen...
ABSTRACT: Fluorescence resonance energy transfer (FRET) has been widely used as a spectroscopic tech...
With the increasing importance of accurate and early disease diagnosis and the development of person...
Nanostructures possess distinct quenching ability toward fluorophores with different emission freque...
Semiconductor nanowires are known to enhance the signal of fluorophores in their proximity. In our r...
The designed synthesis of new nanomaterials with controlled shape, composition, and structure is cri...
Fluorescence is a powerful tool for probing changes in structure on the nanometer scale. Förster res...
The electrochemical detection of nucleic acids using an electrocatalytic reporter system and nanostr...
The designed synthesis of new nanomaterials with controlled shape, composition, and structure is cri...
With the increasing importance of personalized medicine and genomics, biosensors have received consi...
A new category of iron oxide nanoparticles (SAMNs, γ-Fe2O3) allows the intimate chemical and electri...
The excellent performance of a biosensor generally depends on the high signal-to-noise ratio, and th...
Silicon nanowire (SiNW) field effect transistors (FETs) have emerged as powerful sensors for ultrase...
A simple and low-cost fluorescence signal-on sensing strategy has been developed based on functional...
Thesis (Ph.D.)--Boston UniversitySince the first report of single-molecule detection using the biolo...
We describe a novel application for detecting specific single strand DNA sequences using multisegmen...
ABSTRACT: Fluorescence resonance energy transfer (FRET) has been widely used as a spectroscopic tech...
With the increasing importance of accurate and early disease diagnosis and the development of person...
Nanostructures possess distinct quenching ability toward fluorophores with different emission freque...
Semiconductor nanowires are known to enhance the signal of fluorophores in their proximity. In our r...
The designed synthesis of new nanomaterials with controlled shape, composition, and structure is cri...
Fluorescence is a powerful tool for probing changes in structure on the nanometer scale. Förster res...
The electrochemical detection of nucleic acids using an electrocatalytic reporter system and nanostr...
The designed synthesis of new nanomaterials with controlled shape, composition, and structure is cri...
With the increasing importance of personalized medicine and genomics, biosensors have received consi...
A new category of iron oxide nanoparticles (SAMNs, γ-Fe2O3) allows the intimate chemical and electri...
The excellent performance of a biosensor generally depends on the high signal-to-noise ratio, and th...
Silicon nanowire (SiNW) field effect transistors (FETs) have emerged as powerful sensors for ultrase...
A simple and low-cost fluorescence signal-on sensing strategy has been developed based on functional...
Thesis (Ph.D.)--Boston UniversitySince the first report of single-molecule detection using the biolo...
We describe a novel application for detecting specific single strand DNA sequences using multisegmen...
ABSTRACT: Fluorescence resonance energy transfer (FRET) has been widely used as a spectroscopic tech...
With the increasing importance of accurate and early disease diagnosis and the development of person...