Electrophilic aromatic trifluoromethylthiolation with the second generation of trifluoromethanesulfenamide

International audienceDirect trifluoromethylthiolation of various aromatic and heteroaromatic compounds, variously substituted, can be performed with the second generation of trifluoromethanesulfenamide via a ‘Friedel–Crafts-like reaction’. This reaction requires mild conditions with a catalytic amount of protic or Lewis acid. Good results have been obtained, even with aromatic compounds bearing deactivating substituents