International audienceDetection of autoantibodies, which are involved in tissue injury and/or the reporters from the immune system of various pathologic events, has an important potential for diagnosis, prognosis, disease staging and treatment selection. This explains the interest for new proteomics technologies, such as the high-density protein microarray used here, that allow a high-throughput, multiplexed and sensitive detection of specific autoantibodies. So far, most of the research has been performed on blood. In this note, we focus on the cerebrospinal fluid in an attempt to address autoimmune events associated with neurological disorders. Importantly, the cerebrospinal fluid is quite different from the blood in terms of protein comp...
As with the development of any novel and potentially powerful technology, the prospect of revealing ...
represent global health issues. Accordingly, there is an urgent need to understand the pathogenesis ...
This work focus on the generation and application of high-density protein arrays to study autoimmune...
This thesis provides results from affinity based studies where human body fluids were profiled to fi...
Autoantibodies are self-reactive antibodies that have been widely implicated as causal agents of aut...
AbstractSystemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by the prod...
Profiling the autoantibody repertoire with large antigen collections is emerging as a powerful tool ...
<div><p>Autoantibodies in cerebrospinal fluid (CSF) from patients with neuropsychiatric systemic lup...
The brain is a vital organ and because it is well shielded from the outside environment, possibiliti...
Autoantibodies in cerebrospinal fluid (CSF) from patients with neuropsychiatric systemic lupus eryth...
Antibodies are a class of proteins that are made by the immune system to recognize harmful organisms...
There is a great need to increase our understanding of diseases affecting the brain and their underl...
Autoantibodies in cerebrospinal fluid (CSF) from patients with neuropsychiatric systemic lupus eryth...
Proteomics technologies are often used for the identification of protein targets of the immune syste...
Affinity-based proteomics offers opportunities for the discovery and validation of disease-associate...
As with the development of any novel and potentially powerful technology, the prospect of revealing ...
represent global health issues. Accordingly, there is an urgent need to understand the pathogenesis ...
This work focus on the generation and application of high-density protein arrays to study autoimmune...
This thesis provides results from affinity based studies where human body fluids were profiled to fi...
Autoantibodies are self-reactive antibodies that have been widely implicated as causal agents of aut...
AbstractSystemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by the prod...
Profiling the autoantibody repertoire with large antigen collections is emerging as a powerful tool ...
<div><p>Autoantibodies in cerebrospinal fluid (CSF) from patients with neuropsychiatric systemic lup...
The brain is a vital organ and because it is well shielded from the outside environment, possibiliti...
Autoantibodies in cerebrospinal fluid (CSF) from patients with neuropsychiatric systemic lupus eryth...
Antibodies are a class of proteins that are made by the immune system to recognize harmful organisms...
There is a great need to increase our understanding of diseases affecting the brain and their underl...
Autoantibodies in cerebrospinal fluid (CSF) from patients with neuropsychiatric systemic lupus eryth...
Proteomics technologies are often used for the identification of protein targets of the immune syste...
Affinity-based proteomics offers opportunities for the discovery and validation of disease-associate...
As with the development of any novel and potentially powerful technology, the prospect of revealing ...
represent global health issues. Accordingly, there is an urgent need to understand the pathogenesis ...
This work focus on the generation and application of high-density protein arrays to study autoimmune...