BAG-1 is an anti-apoptotic protein that is frequently deregulated in a variety of malignancies including colorectal cancer. There are three isoforms: BAG-1L is located in the nucleus, BAG-1M and BAG-1S are located both in the nucleus and the cytoplasm. In colon cancer, the expression of nuclear BAG-1 is associated with poorer prognosis and is potentially a useful predictive factor for distant metastasis. However, the function of BAG-1 in colonic epithelial cells has not been studied. Having previously shown a predominant nuclear localisation of BAG-1 in adenoma-derived cell lines,1 we wanted to determine the function of nuclear BAG-1 in these non-tumourigenic cells, to identify whether nuclear BAG-1 was implicated in tumour progression in t...
BAG-1 is a multifunctional protein that interacts with a wide range of cellular targets including he...
BAG-1 is multifunctional protein which interacts with a wide range of cellular targets to regulate g...
Stress-induced apoptosis regulates neoplasia pathogenesis and response to therapy. Indeed, cell tran...
Although expression of the anti-apoptotic protein Bcl-2-associated athanogene-1 (BAG-1) has been rep...
Understanding the mechanisms that promote aberrant tumour cell survival is critical for the determin...
Understanding the mechanisms that promote aberrant tumour cell survival is critical for the determin...
BAG-1 is a multifunctional protein that exists as several differentially localised and functionally ...
As colorectal cancer remains the second highest cause of cancer-related deaths in much of the indust...
BAG-1 is a multifunctional protein that binds a wide range of cellular targets including heat shock ...
Bag-1 is an anti-apoptotic protein that promotes metastasis in some tumour cell types. To determine ...
Although the retinoblastoma susceptibility gene RB1 is inactivated in a wide range of human tumours,...
BAG-1 is a multi-functional protein that exists as three functionally distinct and differentially lo...
BAG-1 is a multifunctional protein that blocks apoptosis and interacts with several types of protein...
BAG-1 is a multifunctional protein that interacts with a wide range of target molecules to regulate ...
In oral cancers, cytoplasmic BAG-1 overexpression is a marker of poor prognosis. BAG-1 regulates cel...
BAG-1 is a multifunctional protein that interacts with a wide range of cellular targets including he...
BAG-1 is multifunctional protein which interacts with a wide range of cellular targets to regulate g...
Stress-induced apoptosis regulates neoplasia pathogenesis and response to therapy. Indeed, cell tran...
Although expression of the anti-apoptotic protein Bcl-2-associated athanogene-1 (BAG-1) has been rep...
Understanding the mechanisms that promote aberrant tumour cell survival is critical for the determin...
Understanding the mechanisms that promote aberrant tumour cell survival is critical for the determin...
BAG-1 is a multifunctional protein that exists as several differentially localised and functionally ...
As colorectal cancer remains the second highest cause of cancer-related deaths in much of the indust...
BAG-1 is a multifunctional protein that binds a wide range of cellular targets including heat shock ...
Bag-1 is an anti-apoptotic protein that promotes metastasis in some tumour cell types. To determine ...
Although the retinoblastoma susceptibility gene RB1 is inactivated in a wide range of human tumours,...
BAG-1 is a multi-functional protein that exists as three functionally distinct and differentially lo...
BAG-1 is a multifunctional protein that blocks apoptosis and interacts with several types of protein...
BAG-1 is a multifunctional protein that interacts with a wide range of target molecules to regulate ...
In oral cancers, cytoplasmic BAG-1 overexpression is a marker of poor prognosis. BAG-1 regulates cel...
BAG-1 is a multifunctional protein that interacts with a wide range of cellular targets including he...
BAG-1 is multifunctional protein which interacts with a wide range of cellular targets to regulate g...
Stress-induced apoptosis regulates neoplasia pathogenesis and response to therapy. Indeed, cell tran...