An ideal animal model of atherosclerosis resembles human anatomy and pathophysiology and has the potential to be used in medical and pharmaceutical research to obtain results that can be extrapolated to human medicine. Moreover, it must be easy to acquire, can be maintained at a reasonable cost, is easy to handle and shares the topography of the lesions with humans. In general, animal models of atherosclerosis are based on accelerated plaque formation due to a cholesterol-rich/Western-type diet, manipulation of genes involved in the cholesterol metabolism, and the introduction of additional risk factors for atherosclerosis. Mouse and rabbit models have been mostly used, followed by pigs and non-human primates. Each of these models has its a...
Atherosclerosis and its thrombotic complications are responsible for remarkably high numbers of deat...
Atherothrombotic events such as myocardial infarction and ischemic stroke are a major cause of morbi...
Atherosclerosis and its clinical sequela coronary heart disease is a major cause of death in the mod...
An ideal animal model of atherosclerosis resembles human anatomy and pathophysiology and has the pot...
Cardiovascular disease is the largest single cause of disease-related mortality worldwide and the ma...
Abstract—Atherosclerosis is a chronic inflammatory disorder that is the underlying cause of most car...
Atherosclerosis is a multifactorial highly-complex disease with numerous etiologies that work synerg...
SUMMARY Atherosclerosis is the leading underlying cause of different human cardiovascular diseases,...
Cardiovascular disease is currently the predominant cause of mortality worldwide and its incidence i...
Abstract—There is an urgent need for representative animal models where prospective examination of t...
Atherosclerosis-associated diseases are the main cause of mortality and morbidity in western societi...
Cardiovascular disease,predominantly coronary heart disease and stroke,leads to high morbidity and m...
Atherosclerosis has been studied in animals for almost a century, yet the events leading up to the r...
International audienceAtherosclerosis, the main cause of heart attack and stroke, is the leading cau...
Atherosclerosis-Associated diseases are the main cause ofmortality and morbidity in western societie...
Atherosclerosis and its thrombotic complications are responsible for remarkably high numbers of deat...
Atherothrombotic events such as myocardial infarction and ischemic stroke are a major cause of morbi...
Atherosclerosis and its clinical sequela coronary heart disease is a major cause of death in the mod...
An ideal animal model of atherosclerosis resembles human anatomy and pathophysiology and has the pot...
Cardiovascular disease is the largest single cause of disease-related mortality worldwide and the ma...
Abstract—Atherosclerosis is a chronic inflammatory disorder that is the underlying cause of most car...
Atherosclerosis is a multifactorial highly-complex disease with numerous etiologies that work synerg...
SUMMARY Atherosclerosis is the leading underlying cause of different human cardiovascular diseases,...
Cardiovascular disease is currently the predominant cause of mortality worldwide and its incidence i...
Abstract—There is an urgent need for representative animal models where prospective examination of t...
Atherosclerosis-associated diseases are the main cause of mortality and morbidity in western societi...
Cardiovascular disease,predominantly coronary heart disease and stroke,leads to high morbidity and m...
Atherosclerosis has been studied in animals for almost a century, yet the events leading up to the r...
International audienceAtherosclerosis, the main cause of heart attack and stroke, is the leading cau...
Atherosclerosis-Associated diseases are the main cause ofmortality and morbidity in western societie...
Atherosclerosis and its thrombotic complications are responsible for remarkably high numbers of deat...
Atherothrombotic events such as myocardial infarction and ischemic stroke are a major cause of morbi...
Atherosclerosis and its clinical sequela coronary heart disease is a major cause of death in the mod...