Influence of thiamine injections on the folic acid balance in white rats organism

Gynznu M., Nikolaienko K., Telpis N., Morozova D., Viroliubova A. Influence of thiamine injections on the folic acid balance in white rats organism. Journal of Education, Health and Sport. 2017;7(10):235-238. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1133452 http://ojs.ukw.edu.pl/index.php/johs/article/view/5172 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 1223 (26.01.2017). 1223 Journal of Education, Health and Sport eISSN 2391-8306 7 © The Authors 2017; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 10.10.2017. Revised: 27.10.2017. Accepted: 30.10.2017. Influence of thiamine injections on the folic acid balance in white rats organism M. Gynznu, K. Nikolaienko, N. Telpis, D. Morozova, A. Viroliubova Odessa state basic medical college Odessa I.I. Mechnikov National University Abstract The interaction of thiamine and folic acid in the organism of white rats were carried out under intramuscular injections of thiamine. The research was conducted on 120 white Wistar rats weighing 150-200 g, which were divided into two groups, one was injected with thiamine, and the second was a control group. All animals were obtained the standard ration of the vivarium. After intramuscular injections of thiamine in dose 1 mg/kg mass it was established, that folic acid content after 60-240 min after injection decrease in small intestine and muscles of animals. Meanwhile, this indication in liver and blood increased. These data achieve that thiamine injection leads to changes of folic acid content in different tissues. Key words: thiamine injection, folic acid, metabolism, rats