New Treatment Possibilities in Adolescent Acne

Acne vulgaris jedna je od najčešćih dermatoza uopće. Liječenje je u velike većine bolesnika vrlo uspješno, a ovisi o obliku akne. Kod blažih slučajeva primjenjuje se samo lokalna terapija, a kod srednje teških i teških slučajeva uz lokalnu se istodobno daje i opća terapija. Redovitim čišćenjem kože i lokalnom, danas najčešće kombiniranom, keratolitičkom I antimikrobnom terapijom nastoji se s kože ukloniti pretjerani lipidni sloj, spriječiti začepljenje otvora folikula i stvaranje novih komedona te papula i pustula. Kod srednje teških oblika bolesti uz lokalne terapijske mjere uobičajeno se daju antibiotici, najčešće tetraciklini u nižim dozama ili azitromicin, dok je kod najtežih oblika bolesti i dalje terapija izbora peroralno primijenjen izotretinoin.Acne vulgaris is a polyetiologic disease that affects 80-85% of adolescents. It is also one of the most frequent skin diseases. In most patients acne is a highly treatable disease and depends on a stage of skin changes. In mild cases only topical treatment is sufficient, while in moderate and severe cases local treatment is combined with systemic treatment. Regular skin cleansing together with currently the most frequent combination of topical keratolytic and antimicrobial therapy will remove abundant skin surface lipids, prevent closure of follicular openings and new comedo formations, as well as papules and pustules. In moderate cases topical treatment is combined with oral antibiotics, mostly low-dose tetracyclines or azithromycin, while in severe cases oral isotretinoin remains the treatment of choice