J Clin Hypertens (Greenwich)

BackgroundThe association between OSA and hypertension by race/ethnicity has not been well characterized in a national sample.SubjectsAdult participants in the 2007\ue2\u20ac\u201c2008 National Health and Nutrition Examination Survey.MethodsWe reviewed self-reports of sleep apnea diagnosis, snorting, gasping or stopping breathing during sleep and snoring to derive whether OSA was probable (pOSA). Multivariable logistic regression determined whether pOSA predicted hypertension in the cohort, and BMI and ethno-racial strata.ResultspOSA predicted hypertension in several groups: 1) Within BMI strata, there was a significant association among overweight individuals [OR (95% CI) =1.82 (1.26\ue2\u20ac\u201c2.62)]; 2) In race/ethnicity subgroups, the association was significant among Hispanic/Latinos [OR (95% CI) =1.69 (1.13, 2.53)] and whites [OR (95% CI) =1.40 (1.07, 1.84)]; 3) In models stratified by both race/ethnicity and weight, pOSA predicted hypertension among overweight Black/African Americans [OR (95% CI) =4.74 (1.86\ue2\u20ac\u201c12.03)], overweight whites [OR (95% CI) =1.65 (1.06, 2.57)], and obese Hispanic/Latino participants [OR (95% CI) =2.01 (1.16, 3.49)].ConclusionsA simple, self-report tool for OSA was strongly associated with hypertension, and may serve as a potential future opportunity for OSA diagnosis.K23 HL110216/HL/NHLBI NIH HHS/United StatesK23HL110216/HL/NHLBI NIH HHS/United StatesR01-OH009149/OH/NIOSH CDC HHS/United StatesR21 ES022931/ES/NIEHS NIH HHS/United StatesR21ES022931/ES/NIEHS NIH HHS/United StatesT32HL07713-19/HL/NHLBI NIH HHS/United StatesUL1RR024134/RR/NCRR NIH HHS/United States2014-08-01T00:00:00Z23889723PMC373349