Vertebrate locomotion at different speeds is driven by descending excitatory connections to central pattern generators in the spinal cord. To investigate how these inputs determine locomotor kinematics, we used whole-field visual motion to drive zebrafish to swim at different speeds. Larvae match the stimulus speed by utilizing more locomotor events, or modifying kinematic parameters such as the duration and speed of swimming bouts, the tail-beat frequency, and the choice of gait. We used laser ablations, electrical stimulation, and activity recordings in descending neurons of the nucleus of the medial longitudinal fasciculus (nMLF) to dissect their contribution to controlling forward movement. We found that the activity of single identifie...
Neural networks are the functional building blocks of the central nervous system. To better understa...
A basic question in the field of motor control is how different actions are represented by activity ...
Locomotion relies on neural networks called central pattern generators (CPGs) that generate periodic...
Vertebrate locomotion at different speeds is driven by descending excitatory connections to central ...
SummaryVertebrate locomotion at different speeds is driven by descending excitatory connections to c...
Vertebrate locomotion at different speeds is driven by descending excitatory connections to central ...
Understanding how the central nervous system generates motor sequences, coordinates limbs and body o...
Locomotion is produced by neuronal circuits in the spinal cord. These motor circuits rely on the act...
Locomotor behaviors are critical for survival and enable animals to navigate their environment, find...
Many spinal circuits dedicated to locomotor control have been identified in the developing zebrafish...
Locomotion in vertebrates relies on high brain centers converging onto the mesencephalic locomotor r...
In this issue of Neuron, three papers, Severi et al. (2014), Thiele et al. (2014), and Wang and McLe...
Electrical stimulation of various brainstem nuclei has revealed sites capable of initiating and modu...
SummaryA recent study has used optogenetics to identify the source of excitatory drive for locomotio...
The neural networks that underlie locomotion are complex and require integration of sensory input an...
Neural networks are the functional building blocks of the central nervous system. To better understa...
A basic question in the field of motor control is how different actions are represented by activity ...
Locomotion relies on neural networks called central pattern generators (CPGs) that generate periodic...
Vertebrate locomotion at different speeds is driven by descending excitatory connections to central ...
SummaryVertebrate locomotion at different speeds is driven by descending excitatory connections to c...
Vertebrate locomotion at different speeds is driven by descending excitatory connections to central ...
Understanding how the central nervous system generates motor sequences, coordinates limbs and body o...
Locomotion is produced by neuronal circuits in the spinal cord. These motor circuits rely on the act...
Locomotor behaviors are critical for survival and enable animals to navigate their environment, find...
Many spinal circuits dedicated to locomotor control have been identified in the developing zebrafish...
Locomotion in vertebrates relies on high brain centers converging onto the mesencephalic locomotor r...
In this issue of Neuron, three papers, Severi et al. (2014), Thiele et al. (2014), and Wang and McLe...
Electrical stimulation of various brainstem nuclei has revealed sites capable of initiating and modu...
SummaryA recent study has used optogenetics to identify the source of excitatory drive for locomotio...
The neural networks that underlie locomotion are complex and require integration of sensory input an...
Neural networks are the functional building blocks of the central nervous system. To better understa...
A basic question in the field of motor control is how different actions are represented by activity ...
Locomotion relies on neural networks called central pattern generators (CPGs) that generate periodic...