AIDS Behav

We present a comparison of respondent-driven sampling (RDS) and time-location sampling (TLS) for behavioral surveillance studies among men who have sex with men (MSM). In 2010, we conducted two simultaneous studies using TLS (N = 609) and RDS (N = 507) in Guatemala city. Differences in characteristics of the population reached based on weighted estimates as well as the time and cost of recruitment are presented. RDS MSM were marginally more likely to self-report as heterosexual, less likely to disclose sexual orientation to family members and more likely to report sex with women than TLS MSM. Although RDS MSM were less likely than TLS MSM to report 652 non-commercial male partners, they were more likely to report selling sex in the past 12 months. The cost per participant was $89 and $121 for RDS and TLS, respectively. Our results suggest that RDS reached a more hidden sub-population of non-gay-identifying MSM than TLS and had a lower implementation cost.P30 AI50410/AI/NIAID NIH HHS/United StatesD43 GH000014/GH/CGH CDC HHS/United StatesCC999999/Intramural CDC HHS/United States6D43GH000014-05/GH/CGH CDC HHS/United StatesP30 AI050410/AI/NIAID NIH HHS/United States2017-11-09T00:00:00Z23963498PMC567928