Add to ORKGIntroductionPyrazinamide (PZA) is essential in tuberculosis (TB) treatment. We describe the prevalence, trends and predictors of PZA resistance in Mycobacterium tuberculosis complex (MTBC) in the U.S.MethodsWe analyzed culture-positive MTBC cases with reported drug susceptibility tests (DST) for PZA in 38 jurisdictions routinely testing for PZA susceptibility from 1999-2009. National TB Genotyping Service data for 2004-2009 were used to distinguish Mycobacterium tuberculosis from Mycobacterium bovis and determine phylogenetic lineage.ResultsOverall 2.7% (2,167/79,321) of MTBC cases had PZA resistance, increasing annually from 2.0% to 3.3% during 1999-2009 (P<0.001), largely due to an increase in PZA monoresistance. PZA-monoresistant MTBC (v...
Introduction: Multidrug-Resistant Tuberculosis (MDR-TB) is a growing concern which has always played...
Abstract Background Tuberculosis (TB) is the leading cause of death from an infectious disease and t...
Abstract Background The ongoing epidemic of multidrug-resistant tuberculosis (MDR-TB) in Georgia hig...
BackgroundPyrazinamide (PZA) is crucial for tuberculosis (TB) treatment, given its unique ability to...
BACKGROUND: The ongoing epidemic of multidrug-resistant tuberculosis (MDR-TB) in Georgia highlights ...
Background Pyrazinamide (PZA) is crucial for tuberculosis (TB) treatment, given its unique ability t...
Pyrazinamide resistance is largely unknown in the spectrum of drug resistant phenotypes. We summariz...
Background: Pyrazinamide (PZA) is a first line agent for the treatment of active tuberculosis. PZA i...
Pyrazinamide (PZA) is crucial for tuberculosis (TB) treatment, given its unique ability to eradicate...
AbstractAims and objectivesThe aim of this study is to determine the prevalence of pyrazinamide (PZA...
SETTING: The World Health Organization (WHO) recommends the inclusion of pyrazinamide (PZA) in treat...
Pyrazinamide (PZA) is an essential first-line tuberculosis drug for its unique mechanism of action a...
BACKGROUND: Tuberculosis (TB) is a major global health problem and drug resistance compromises the e...
Pyrazinamide is one of the four first line drugs for treatment of tuberculosis. It has been widely a...
Includes bibliographical references (pages 47-56).Pyrazinamide (PZA) is an important first-line drug...
Introduction: Multidrug-Resistant Tuberculosis (MDR-TB) is a growing concern which has always played...
Abstract Background Tuberculosis (TB) is the leading cause of death from an infectious disease and t...
Abstract Background The ongoing epidemic of multidrug-resistant tuberculosis (MDR-TB) in Georgia hig...
BackgroundPyrazinamide (PZA) is crucial for tuberculosis (TB) treatment, given its unique ability to...
BACKGROUND: The ongoing epidemic of multidrug-resistant tuberculosis (MDR-TB) in Georgia highlights ...
Background Pyrazinamide (PZA) is crucial for tuberculosis (TB) treatment, given its unique ability t...
Pyrazinamide resistance is largely unknown in the spectrum of drug resistant phenotypes. We summariz...
Background: Pyrazinamide (PZA) is a first line agent for the treatment of active tuberculosis. PZA i...
Pyrazinamide (PZA) is crucial for tuberculosis (TB) treatment, given its unique ability to eradicate...
AbstractAims and objectivesThe aim of this study is to determine the prevalence of pyrazinamide (PZA...
SETTING: The World Health Organization (WHO) recommends the inclusion of pyrazinamide (PZA) in treat...
Pyrazinamide (PZA) is an essential first-line tuberculosis drug for its unique mechanism of action a...
BACKGROUND: Tuberculosis (TB) is a major global health problem and drug resistance compromises the e...
Pyrazinamide is one of the four first line drugs for treatment of tuberculosis. It has been widely a...
Includes bibliographical references (pages 47-56).Pyrazinamide (PZA) is an important first-line drug...
Introduction: Multidrug-Resistant Tuberculosis (MDR-TB) is a growing concern which has always played...
Abstract Background Tuberculosis (TB) is the leading cause of death from an infectious disease and t...
Abstract Background The ongoing epidemic of multidrug-resistant tuberculosis (MDR-TB) in Georgia hig...