Add to ORKGRecent advances in cell reprogramming have permitted the development of different stem cell lines and specific differentiated cell types using distinct technologies. Cell reprogramming is largely mediated by DNA and RNA. In this review, we explore the RNA-mediated cell reprogramming to induce specific target cell generation including stem cells, brain cells and cardiac cells. The ability of RNA populations to produce direct cell to cell phenotypic conversion is called Transcriptome Induced PhenotypeRemodeling (TIPeR). The theory and utility of RNA use for cellular reprogramming is explored in this review.DP004117/DP/NCCDPHP CDC HHS/United StatesDP1 OD004117/OD/NIH HHS/United StatesDP1 OD004117-05/OD/NIH HHS/United States2013-05-01T00:00:00Z...
Modified mRNA (modRNA)-based somatic reprogramming is an effective and safe approach that overcomes ...
Cellular reprogramming technology holds great potential for tissue repair and regeneration to replac...
SummaryClinical application of induced pluripotent stem cells (iPSCs) is limited by the low efficien...
Cell therapy approaches to treat a wide range of pathologies have greatly benefited from cell reprog...
The therapeutic potential of induced pluripotent stem cells (iPSCs) is well established. Safety conc...
Cell reprogramming is a groundbreaking technology that, in few decades, generated a new paradigm in ...
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer...
Cellular reprogramming by epigenomic remodeling of chromatin holds great promise in the field of hum...
International audienceReprogramming is the ability to change the fate of a cell to another one. A sc...
Introduction of four transcription factors, Oct3/4, Sox2, Klf4, and c-Myc, can successfully reprogra...
Abstract The therapeutic potential of induced pluripotent stem cells (iPSCs) is well established. Sa...
Cellular differentiation and development appears as a unidirectional process to specific cell fates ...
Noncoding RNAs have emerged as important determinants of pluripotency and reprogramming. In this iss...
Stem cells have revolutionized research and applications for biomedical sciences. In combination wit...
Generating needed cell types using cellular reprogramming is a promising strategy for restoring tiss...
Modified mRNA (modRNA)-based somatic reprogramming is an effective and safe approach that overcomes ...
Cellular reprogramming technology holds great potential for tissue repair and regeneration to replac...
SummaryClinical application of induced pluripotent stem cells (iPSCs) is limited by the low efficien...
Cell therapy approaches to treat a wide range of pathologies have greatly benefited from cell reprog...
The therapeutic potential of induced pluripotent stem cells (iPSCs) is well established. Safety conc...
Cell reprogramming is a groundbreaking technology that, in few decades, generated a new paradigm in ...
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer...
Cellular reprogramming by epigenomic remodeling of chromatin holds great promise in the field of hum...
International audienceReprogramming is the ability to change the fate of a cell to another one. A sc...
Introduction of four transcription factors, Oct3/4, Sox2, Klf4, and c-Myc, can successfully reprogra...
Abstract The therapeutic potential of induced pluripotent stem cells (iPSCs) is well established. Sa...
Cellular differentiation and development appears as a unidirectional process to specific cell fates ...
Noncoding RNAs have emerged as important determinants of pluripotency and reprogramming. In this iss...
Stem cells have revolutionized research and applications for biomedical sciences. In combination wit...
Generating needed cell types using cellular reprogramming is a promising strategy for restoring tiss...
Modified mRNA (modRNA)-based somatic reprogramming is an effective and safe approach that overcomes ...
Cellular reprogramming technology holds great potential for tissue repair and regeneration to replac...
SummaryClinical application of induced pluripotent stem cells (iPSCs) is limited by the low efficien...