Abstract Exposure to amphibole asbestos has been associated with production of autoantibodies in mice and humans, and increases the risk of systemic autoimmune disease. However, epidemiological studies of chrysotile exposure have not indicated a similar induction of autoimmune responses. To demonstrate this difference in controlled exposures in mice, and to explore possible mechanistic explanations for the difference, C57BL/6 mice were exposed intratracheally to amphibole or chrysotile asbestos, or to saline only. Serum antinuclear antibodies (ANA), antibodies to extractable nuclear antigens (ENA), serum cytokines, and immunoglobulin isotypes were evaluated 8 months after the final treatment. The percentages of lymphocyte sub-sets were dete...
Fluoro-edenite (FE) is an asbestiform mineral fiber spotted in the lava rocks excavated from a stone...
Fluoro-edenite (FE) is an asbestiform mineral fiber spotted in the lava rocks excavated from a stone...
Systemic autoimmune responses are associated with certain environmental exposures, including crystal...
Despite a body of evidence supporting an association between asbestos exposure and autoantibodies in...
Asbestos are naturally occurring fibers found in rock outcroppings but also used in many commercial ...
An increased risk for Systemic Autoimmune Diseases (SAID) was reported in the population of Libby, M...
Environmental exposure to silicate compounds such as silica and asbestos has been associated with in...
The role of the macrophage in asbestos induced autoantibody production Chairperson: Michael F. Minni...
Several lines of evidence have suggested that specific (i.e., lymphocyte) immunity plays a role in c...
which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
Despite data linking amphibole asbestos exposure with production of autoantibodies, the role of auto...
Balb/c mice were exposed to aerosolized chrysotile fibers and evaluated as a host for the study of a...
Balb/c mice were exposed to aerosolized chrysotile fibers and evaluated as a host for the study of a...
Balb/c mice were exposed to aerosolized chrysotile fibers and evaluated as a host for the study of a...
Asbestos fibers cause malignant tumors such as lung cancer and malignant mesothelioma. Furthermore, ...
Fluoro-edenite (FE) is an asbestiform mineral fiber spotted in the lava rocks excavated from a stone...
Fluoro-edenite (FE) is an asbestiform mineral fiber spotted in the lava rocks excavated from a stone...
Systemic autoimmune responses are associated with certain environmental exposures, including crystal...
Despite a body of evidence supporting an association between asbestos exposure and autoantibodies in...
Asbestos are naturally occurring fibers found in rock outcroppings but also used in many commercial ...
An increased risk for Systemic Autoimmune Diseases (SAID) was reported in the population of Libby, M...
Environmental exposure to silicate compounds such as silica and asbestos has been associated with in...
The role of the macrophage in asbestos induced autoantibody production Chairperson: Michael F. Minni...
Several lines of evidence have suggested that specific (i.e., lymphocyte) immunity plays a role in c...
which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
Despite data linking amphibole asbestos exposure with production of autoantibodies, the role of auto...
Balb/c mice were exposed to aerosolized chrysotile fibers and evaluated as a host for the study of a...
Balb/c mice were exposed to aerosolized chrysotile fibers and evaluated as a host for the study of a...
Balb/c mice were exposed to aerosolized chrysotile fibers and evaluated as a host for the study of a...
Asbestos fibers cause malignant tumors such as lung cancer and malignant mesothelioma. Furthermore, ...
Fluoro-edenite (FE) is an asbestiform mineral fiber spotted in the lava rocks excavated from a stone...
Fluoro-edenite (FE) is an asbestiform mineral fiber spotted in the lava rocks excavated from a stone...
Systemic autoimmune responses are associated with certain environmental exposures, including crystal...