Intermittent preventive treatment during pregnancy with sulfadoxine-pyrimethamine (IPTp-SP) is a key strategy in the control of pregnancy-associated malaria. However, this strategy is compromised by widespread drug resistance from single-nucleotide polymorphisms in the Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthetase genes. During September 2008-October 2010, we monitored a cohort of 924 pregnant women in an area of Tanzania with declining malaria transmission. P. falciparum parasites were genotyped, and the effect of infecting haplotypes on birthweight was assessed. Of the genotyped parasites, 9.3%, 46.3%, and 44.4% had quadruple or less, quintuple, and sextuple mutated haplotypes, respectively. Mutant haplotype...
International audienceIntermittent preventive treatment in pregnancy with sulfadoxine and pyrimetham...
International audienceIntermittent preventive treatment in pregnancy with sulfadoxine and pyrimetham...
Sulfadoxine-pyrimethamine (SP) has been widely deployed in Africa for malaria control and molecular ...
Intermittent preventive treatment during pregnancy with sulfadoxine–pyrimethamine (IPTp-SP) is a key...
BackgroundResistance to sulphadoxine-pyrimethamine (SP) in Plasmodium falciparum parasites is associ...
Malaria remains one of the most preventable causes of adverse birth outcomes. Intermittent preventiv...
Intermittent preventive treatment in pregnancy (IPTp) with monthly sulfadoxine-pyrimethamine (SP) is...
BackgroundThe effectiveness of sulphadoxine-pyrimethamine (SP) intermittent preventive treatment of ...
Background The A581G mutation in the gene encoding Plasmodium falciparum dihydropteroate synthase...
Pregnant women are a high risk group forPlasmodium falciparuminfections,which may result in maternal...
Malaria remains one of the most preventable causes of adverse birth outcomes. Intermittent preventiv...
Malaria remains one of the most preventable causes of adverse birth outcomes. Intermittent preventiv...
International audienceIntermittent preventive treatment in pregnancy with sulfadoxine and pyrimetham...
In the context of an Intermittent preventive treatment (IPTp) trial for pregnant women in Malawi, P....
International audienceIntermittent preventive treatment in pregnancy with sulfadoxine and pyrimetham...
International audienceIntermittent preventive treatment in pregnancy with sulfadoxine and pyrimetham...
International audienceIntermittent preventive treatment in pregnancy with sulfadoxine and pyrimetham...
Sulfadoxine-pyrimethamine (SP) has been widely deployed in Africa for malaria control and molecular ...
Intermittent preventive treatment during pregnancy with sulfadoxine–pyrimethamine (IPTp-SP) is a key...
BackgroundResistance to sulphadoxine-pyrimethamine (SP) in Plasmodium falciparum parasites is associ...
Malaria remains one of the most preventable causes of adverse birth outcomes. Intermittent preventiv...
Intermittent preventive treatment in pregnancy (IPTp) with monthly sulfadoxine-pyrimethamine (SP) is...
BackgroundThe effectiveness of sulphadoxine-pyrimethamine (SP) intermittent preventive treatment of ...
Background The A581G mutation in the gene encoding Plasmodium falciparum dihydropteroate synthase...
Pregnant women are a high risk group forPlasmodium falciparuminfections,which may result in maternal...
Malaria remains one of the most preventable causes of adverse birth outcomes. Intermittent preventiv...
Malaria remains one of the most preventable causes of adverse birth outcomes. Intermittent preventiv...
International audienceIntermittent preventive treatment in pregnancy with sulfadoxine and pyrimetham...
In the context of an Intermittent preventive treatment (IPTp) trial for pregnant women in Malawi, P....
International audienceIntermittent preventive treatment in pregnancy with sulfadoxine and pyrimetham...
International audienceIntermittent preventive treatment in pregnancy with sulfadoxine and pyrimetham...
International audienceIntermittent preventive treatment in pregnancy with sulfadoxine and pyrimetham...
Sulfadoxine-pyrimethamine (SP) has been widely deployed in Africa for malaria control and molecular ...