Prevalence of cigarette smoking in patients with various laryngeal diseases

Uvod: Pušenje cigareta je važan predominantni faktor u laringealnoj karcinogenezi. Cilj rada je prikazati ucestalost pušenja cigareta kod razlicitih oboljenja larinksa. Metoda rada: U radu smo analizirali ucestalost pušenja u svih bolesnika u kojih je bila indicirana izravna mikrolaringoskopija na ORL odjelu KB Split u razdoblju od dvije godine. Rezultati su prikazani u tablicama, a analizirani su metodom studentovog t-testa i 2 testa. Rezultati: Radom je obuhvacena skupina od 281 bolesnika, koje smo svrstali u tri grupe: grupa 1 – benigne promjene, grupa 2 – prekancerozne promjene, grupa 3 – zlocudni tumori. Vecina bolesnika su dugogodišnji pušaci (82,92%). Najmanje pušaca bilo je u grupi 1 (72,13%), u grupi 2 bilo ih je 81,48%, a najviše u grupi 3 – 97,14%. Postoji statisticki znacajna razlika u ucestalosti pušenja bolesnika sa zlocudnim tumorom larinksa i bolesnika s benignom ili prekanceroznom promjenom (p < 0,01). Zakljucak: Prikazani rezultati jasno ukazuju na povecanu ucestalost oboljenja larinksa u pušaca, ali i znacajnu statisticku razliku o ucestalosti pušenja u bolesnika s benignim promjenama larinksa u odnosu na bolesnike sa zlocudnim tumorom larinksa.Introduction. Cigarette smoking is a major factor of laryngeal carcinogenesis. The aim was to assess the prevalence of the cigarette smoking habit in patients with various laryngeal diseases. Methods. Data on all patients with indications for direct microlaryngoscopy at ENT Department, Split University Hospital Center, during a two-year period were analyzed. Results were processed by student t-test and 2 test and are presented in the tables. Results. The study included 281 patients, divided into three groups as follows: group 1, benign lesions; group 2, precancerous lesions; and group 3, malignant tumors. The majority of patients (82.92%) had a long history of smoking. The proportion of smokers was lowest in group 1 (72.13%), higher in group 2 (81.48%) and the highest in group 3 (97.14%). There was a statistically significant difference in the prevalence of cigarette smoking between patients with malignant laryngeal tumors and those with benign or precancerous lesions (p < 0.01). Conclusion. Study results clearly pointed to the increased prevalence of laryngeal diseases in smokers, with a statistically significant difference between patients with benign laryngeal lesions and those with malignant laryngeal tumors