Central Low-Grade Mucoepidermoid Carcinoma or Glandular Odontogenic Cyst: Report of an Interesting Case

Mukoepidermoidni karcinom rijedak je u čeljusti i histološki je jako varijabilan. Točna patogeneza nije poznata - hipoteza je da epitelna ovojnica odontogene ciste ima najvažniju zadaću. Budući da je malo oralnih patologa i kliničara vidjelo tu leziju, potrebno je odrediti kliničko-patološke parametre i kriterije za postavljanje dijagnoze. U ovom radu izvještavamo o centralnom mukoepidermoidnom karcinomu niskog stupnja kod 46-godišnjeg muškarca te opisujemo kliničko-patološka svojstva i raspravljamo o sličnosti sa žljezdanom odontogenom cistom (GOC-om). Svjetska zdravstvena organizacija proglasila je GOC neovisnim patološkim entitetom i klasificirala ga kao razvojnu odontogenu epitelnu cistu.Mucoepidermoid carcinoma occurring centrally within the jaws is a rare lesion which exhibits considerable histologic variability. The exact pathogenesis is unknown; the hypothesis is that the epithelial linings of odontogenic cysts play most important part. Since many oral pathologists and clinicians seldom encounter this lesion, criteria for diagnosis and clinico-pathological guidelines are considered necessary. We report an additional case of central low grade mucoepidermoid carcinoma occurring in a 46 yr old male patient and describe its clinico-pathologic features and discuss the similarity to the glandular odontogenic cyst (GOC). The World Health Organization has named GOC as an independent pathologic entity and classified it as a developmental odontogenic epithelial cyst