Stack and measurement of zeptomole neurotransmitters released from living single cells on a FASS-nano-fluidic chip with electrochemical detection

[[abstract]]This paper demonstrates the detection possibility of zeptomole level neurotransmitters released from two to three living PC-12 cells by employing FASS (the Field-amplified sample stacking) incorporated with a nano Pd-Pt-SWCNT (Pd-Pt nanostructure modified Single-wall carbon nanotube) electrode and integrated on a nano EC-CE (electrochemical capillairy electrophoresis) chip. The detection limit can approach 0.5 nM (? 38 zeptomole) dopamine with an S/N ratio > 2 for the releasing from two-three living cells