Genital Human Papillomavirus Infections

Infekcija humanim papilomavirusom (HPV) jedna je od najčešćih spolno prenosivih bolesti virusne etiologije. Infekcije HPV-om povezane su s različitim promjenama, od benignih veruka, akuminiranih kondiloma pa sve do malignih karcinoma cerviksa, vulve, vagine, penisa i anusa. Muškarci su obično rezervoar virusa koji se najčešće nalazi u genitalnim sluznicama u latentnom i supkliničkom obliku, stoga asimptomatske infekcije mogu biti onkogeni faktor(i) u razvoju cervikalnog karcinoma. Pregled genitalne regije muškaraca nakon aplikacije 3-5%-tne octene kiseline pod povećanjem kolposkopa važan je dijagnostički postupak u obradi muškaraca s asimptomatskom i/ili latentnom infekcijom. Dijagnoza i liječenje HPV-infekcije u muškaraca su važni jer eradikacija HPV-infekcija penisa može smanjiti rezervoar virusa.Genital human papillomavirus (HPV) infections are one of the most common sexually transmitted disease of viral origin. HPV is associated with a spectrum of diseases, ranging from benign verruca vulgaris and condylomata acuminate, to malignant cervical, vulvar, vaginal, anal or penile cancer. Men are usually the reservoir of the virus, which lives in latent or subclinical form on genital mucosa, and these asymptomatic infections can be oncogenic factor(s) in the development of cervical cancer. The examination of genital region in men, after application of 3-5% acetic acid, and use of colposcope is a reliable method for identifi cation of subclinical HPV infections. The diagnosis and therapy of HPV infection in men is a potential benefi t, because eradication of penile HPV infection may decrease the reservoir of the virus