Korelacija koštane mineralne gustoće mjerene kvalitativnim ultrazvukom i dvoenergetskom rendgenskom apsorpciometrijom

Osteoporosis is a systemic skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue, with consequential increase in bone fragility and susceptibility to fracture. Bone mineral density (BMD) is an important determinant factor of fracture risk. Fifty-eight healthy postmenopausal women aged 53-91 years were included in the study. The subjects were divided into three age groups. Heel bone (calcaneus) BMD detected by qualitative ultrasound (QUS) was correlated with lumbar spine and proximal femur BMD detected by dual energy x-ray absorptiometry (DEXA). Also, subject age and anthropometric parameters (body weight and height) were correlated with BMD values in the calcaneus, spine and proximal femur. A chart was made of T-score conversion for lumbar spine according to T-score of heel bone detected by QUS. Calcaneal BMD showed best correlation in group 2 (58-67 yrs) with total femoral BMD (R=0.72) and intertrochanteric area (R=0.719), both statistically significant (p1=0.0007, p1<0.001; p2=0.0008, p2<0.001). There was no significant correlation between any of the calculated BMD values (calcaneus, lumbar spine and proximal femur) and age, body weight or body height. According to our conversion chart, when T-score calculated on ultrasound densitometry is equal or below -1 it yields a final T-score of lumbar spine between -1 and -2.5, which according to WHO criteria is diagnosed as osteopenia. This makes ultrasound densitometry an excellent screening method to identify patients at a risk of fracture.Osteoporoza je sistemska skeletna bolest obilježena malom koštanom masom i mikroarhitektonskim pogoršanjem koštanoga tkiva, s posljedičnim porastom krhkosti kostiju i sklonosti za prijelome. Koštana mineralna gustoća (BMD) je važan čimbenik koji određuje rizik od prijeloma. Ispitivanje je provedeno u 58 zdravih žena u postmenopauzi, u dobi od 53 do 91 godine. Ispitanice su bile podijeljene u tri dobne skupine. BMD petne kosti (kalkaneus) izmjerena kvalitativnim ultrazvukom (QUS) korelirana je s BMD lumbalne kralješnice i proksimalnog femura izmjerenom dvoenergijskom rendgenskom apsorpciometrijom (DEXA). Također su dob i antropometrijski parametri (tjelesna težina i visina) korelirani s vrijednostima BMD za kalkaneus, kralješnicu i proksimalni femur. Izrađena je vlastita tablica za konverziju T-vrijednosti za lumbalnu kralješnicu prema T-vrijednosti za petnu kost izmjerenima pomoću QUS. Najbolja korelacija za BMD kalkaneusa nađena je u 2. skupini (58-67 godina) s ukupnim BMD femura (R=0,72) i intertrohanterskog područja (R=0,719), obje statistički značajne (p1=0,0007, p1<0,001; p2=0,0008, p2