Survival in very preterm infants: an international comparison of 10 National Neonatal Networks

Helenius, Kjell K
Sjörs, Gunnar
Shah, Prakesh S
Modi, Neena
Reichman, Brian
Morisaki, Naho
Kusuda, Satoshi
Lui, Kei
Darlow, Brian A
Bassler, Dirk
Håkansson, Stellan
Adams, Mark
Vento, Maximo
Rusconi, Franca
Isayama, Tetsuya
Lee, Shoo K
Lehtonen, Liisa
International Network for Evaluating Outcomes (iNeo) of Neonates

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Publication date

December 2017

DOI

10.1542/peds.2017-1264

Publisher

American Academy of Pediatrics

ISSN

0031-4005

Abstract

OBJECTIVES: To compare survival rates and age at death among very preterm infants in 10 national and regional neonatal networks. METHODS: A cohort study of very preterm infants, born between 24 and 29 weeks' gestation and weighing <1500 g, admitted to participating neonatal units between 2007 and 2013 in the International Network for Evaluating Outcomes of Neonates. Survival was compared by using standardized ratios (SRs) comparing survival in each network to the survival estimate of the whole population. RESULTS: Network populations differed with respect to rates of cesarean birth, exposure to antenatal steroids and birth in nontertiary hospitals. Network SRs for survival were highest in Japan (SR: 1.10; 99% confidence interval: 1.08-1.1...