Atherosclerosis is most often the main underlying cause of cardiovascular diseases (CVDs), accounting for more than 31% of all deaths worldwide. It is driven by the uptake of low-density lipoproteins (LDL) by a dysfunctional arterial endothelium. It involves a complex interplay of genetic and cellular factors that result in an uncontrolled inflammatory response which can potentially be fatal. The main treatment for atherosclerosis is cholesterol-lowering drugs, statins. Despite their use, clinical events still occur. In this thesis, three papers regarding CVDs and some of the key events happening during atherosclerosis are discussed. In paper I the role of Lim domain-binding 2 (Ldb2) as a master regulator of transendothelial migratio...
Mechanisms responsible for atherosclerotic plaque development, destabilization, and rupture are stil...
Cardiovascular disease is the main cause of death in the world. The underlying cause in most cases i...
People with diabetes have an increased risk of developing cardiovascular diseases (CVD), such as hea...
Atherosclerosis is a progressive disease of the large arteries characterized by lipid deposition, in...
Atherosclerosis is a cardiovascular inflammatory disease that occurs in major arteries and leads to ...
The work described in this thesis was aimed at identifying the role of cell cycle and apoptosis gene...
BACKGROUND: Atherosclerosis is a leading cause of vascular disease worldwide. During the past severa...
Atherosclerosis is a chronic lipid-driven and maladaptive inflammatory disease of arterial intima. I...
Cardiovascular diseases (CVD), which are mainly caused by the development of atherosclerosis, are th...
Atherosclerosis is a multifactorial, smoldering, focal (intima of bifurcated blood arteries), chroni...
In this thesis the role of several apoptosis regulating proteins in the development of atheroscleros...
Atherosclerosis is a multifactorial disease triggered and sustained by different risk factors such a...
The traditional view of atherosclerosis as a pathological lipid deposition within the artery wall ha...
Atherosclerotic cardiovascular disease (CVD) is the leading cause of mortality worldwide. Atheroscle...
Seminal studies from Nikolai Anichckov identified the accumulation of cholesterol in the arteries as...
Mechanisms responsible for atherosclerotic plaque development, destabilization, and rupture are stil...
Cardiovascular disease is the main cause of death in the world. The underlying cause in most cases i...
People with diabetes have an increased risk of developing cardiovascular diseases (CVD), such as hea...
Atherosclerosis is a progressive disease of the large arteries characterized by lipid deposition, in...
Atherosclerosis is a cardiovascular inflammatory disease that occurs in major arteries and leads to ...
The work described in this thesis was aimed at identifying the role of cell cycle and apoptosis gene...
BACKGROUND: Atherosclerosis is a leading cause of vascular disease worldwide. During the past severa...
Atherosclerosis is a chronic lipid-driven and maladaptive inflammatory disease of arterial intima. I...
Cardiovascular diseases (CVD), which are mainly caused by the development of atherosclerosis, are th...
Atherosclerosis is a multifactorial, smoldering, focal (intima of bifurcated blood arteries), chroni...
In this thesis the role of several apoptosis regulating proteins in the development of atheroscleros...
Atherosclerosis is a multifactorial disease triggered and sustained by different risk factors such a...
The traditional view of atherosclerosis as a pathological lipid deposition within the artery wall ha...
Atherosclerotic cardiovascular disease (CVD) is the leading cause of mortality worldwide. Atheroscle...
Seminal studies from Nikolai Anichckov identified the accumulation of cholesterol in the arteries as...
Mechanisms responsible for atherosclerotic plaque development, destabilization, and rupture are stil...
Cardiovascular disease is the main cause of death in the world. The underlying cause in most cases i...
People with diabetes have an increased risk of developing cardiovascular diseases (CVD), such as hea...