Tissue engineering is an emerging multidisciplinary field that aims at reproducing in vitro and/or in vivo tissues with morphological and functional features similar to the biological tissue of the human body. In this communication we report setting of three-dimensional structures able to mimic the extracellular matrix of the nervous system: we prepared Poly-L-Lactic Acid (PLLA) porous scaffolds via thermally induced phase separation (TIPS), and investigated the parameters that influence porosity, average pore size and degree of interconnection, i.e. polymer concentration, temperature and time of process. Astrocytes and brain capillary endothelial cells (BCECs) were cultured on these three-dimensional structures and tested for their ...
AbstractOpen pores to maintain nutrient diffusion and waste removal after cell colonization are cruc...
Two-dimensional vs three-dimensional culture conditions, such as the presence of extracellular matri...
We tested the hypothesis that astrocytes grown in a suitable three-dimensional (3D) cell culture sys...
Tissue engineering is an emerging multidisciplinary field that aims at reproducing in vitro tissues ...
Tissue engineering is an emerging multidisciplinary field that aims at reproducing in vitro and/or i...
The present study analyzed the ability of primary rat astrocytes to colonize a porous scaffold, mimi...
The brain capillary endothelial cells (BCECs) form the blood brain barrier (BBB) under the effects o...
Open pores to maintain nutrient diffusion and waste removal after cell colonization are crucial for ...
The culture of cells in flat, stiff, two-dimensional environments often results in cells dissimilar ...
At the gliovascular interface, reciprocal inductive influences between brain microvascular endotheli...
Tissue engineering is a branch of regenerative medicine, which comprises the combination of biomater...
This study investigates the utility of a tailored poly(ethylene glycol) diacrylate-crosslinked porou...
The lack of a vascular network and poor perfusion is what mostly prevents three-dimensional (3D) sca...
Objectives: The selection of a good quality scaffold is an essential strategy for tissue engineering...
The mammalian central nervous system (CNS) has limited intrinsic repair mechanisms. Damage or trauma...
AbstractOpen pores to maintain nutrient diffusion and waste removal after cell colonization are cruc...
Two-dimensional vs three-dimensional culture conditions, such as the presence of extracellular matri...
We tested the hypothesis that astrocytes grown in a suitable three-dimensional (3D) cell culture sys...
Tissue engineering is an emerging multidisciplinary field that aims at reproducing in vitro tissues ...
Tissue engineering is an emerging multidisciplinary field that aims at reproducing in vitro and/or i...
The present study analyzed the ability of primary rat astrocytes to colonize a porous scaffold, mimi...
The brain capillary endothelial cells (BCECs) form the blood brain barrier (BBB) under the effects o...
Open pores to maintain nutrient diffusion and waste removal after cell colonization are crucial for ...
The culture of cells in flat, stiff, two-dimensional environments often results in cells dissimilar ...
At the gliovascular interface, reciprocal inductive influences between brain microvascular endotheli...
Tissue engineering is a branch of regenerative medicine, which comprises the combination of biomater...
This study investigates the utility of a tailored poly(ethylene glycol) diacrylate-crosslinked porou...
The lack of a vascular network and poor perfusion is what mostly prevents three-dimensional (3D) sca...
Objectives: The selection of a good quality scaffold is an essential strategy for tissue engineering...
The mammalian central nervous system (CNS) has limited intrinsic repair mechanisms. Damage or trauma...
AbstractOpen pores to maintain nutrient diffusion and waste removal after cell colonization are cruc...
Two-dimensional vs three-dimensional culture conditions, such as the presence of extracellular matri...
We tested the hypothesis that astrocytes grown in a suitable three-dimensional (3D) cell culture sys...