Measurement of liver function using hepatobiliary scintigraphy improves risk assessment in patients undergoing major liver resection
- Cieslak, Kasia P.
- Bennink, Roelof J.
- de Graaf, Wilmar
- van Lienden, Krijn P.
- Besselink, Marc G.
- Busch, Olivier R. C.
- Gouma, Dirk J.
- van Gulik, Thomas M.
DOIAbstract
(99m)Tc-mebrofenin-hepatobiliary-scintigraphy (HBS) enables measurement of future remnant liver (FRL)-function and was implemented in our preoperative routine after calculation of the cut-off value for prediction of postoperative liver failure (LF). This study evaluates our results since the implementation of HBS. Additionally, CT-volumetric methods of FRL-assessment, standardized liver volumetry and FRL/body-weight ratio (FRL-BWR), were evaluated. 163 patients who underwent major liver resection were included. Insufficient FRL-volume and/or FRL-function <2.7%/min/m(2) were indications for portal vein embolization (PVE). Non-PVE patients were compared with a historical cohort (n = 55). Primary endpoints were postoperative LF and LF related ...
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