Background: Interleukin-10 (IL-10) is a negative regulator of immune responses and was previously shown to be expressed by human nasal endothelial cells, while the adhesion molecule MECA-79 plays a role in trans-endothelial migration of immune competent cells. In this study we investigate the relationship between endothelial IL-10 and MECA-79 expression to address the question whether immune competent cells could be affected at the mucosal entry site. Methods: Nasal turbinate biopsies were taken from house dust mite allergic patients, before and after nasal allergen provocation. Subsequent slides of biopsies were stained for IL10, MECA-79, CD34, and IL10-Receptor. Capillaries, arteries/veins, and sinusoids were evaluated separately. Results...
Background: The role of Th2 type cytokines in the persistence of chronic rhinosinusitis, especially ...
BACKGROUND: Allergic rhinitis is an inflammatory disease of the upper airway mucosa that also affect...
Background: Chronic rhinosinusitis (CRS) is characterized by local inflammation of the sinonasal tis...
Accumulating evidence supports the importance of leukocyte-endothelial cell adhesion molecule (CAM) ...
<p>The expression of TSLP, IL-25, IL-33, IL-4, IL-5, IL-9 and IL-13 in nasal tissues derived from pa...
Interleukin 10 (IL-10) is a potent anti-inflammatory cytokine. The dysregulation of IL-10 is associa...
Background: Innate immune recognition via Toll-like receptors (TLRs) on barrier cells like epithelia...
BACKGROUND: Allergic inflammation is regulated by the local production and release of several cytoki...
Understanding the function of the nasal vasculature in homeostasis and pathogenesis of common nasal ...
Allergic and infectious rhinitis are prevalent conditions that besides a direct morbidity also cause...
<div><p>Background and Objectives</p><p>Interleukin 10 (IL-10) is a potent anti-inflammatory cytokin...
BACKGROUND: In allergic diseases, like in rhinitis, antigen challenge induces rapid degranulation of...
Background: IL-10 is a major anti-inflammatory cytokine that prevents inflammation-mediated tissue d...
BACKGROUND: Allergic rhinitis (AR) and asthma are characterized by means of a similar inflammatory p...
Although initially described as an immunomodulatory cytokine, interleukin-10 (IL-10) has also been p...
Background: The role of Th2 type cytokines in the persistence of chronic rhinosinusitis, especially ...
BACKGROUND: Allergic rhinitis is an inflammatory disease of the upper airway mucosa that also affect...
Background: Chronic rhinosinusitis (CRS) is characterized by local inflammation of the sinonasal tis...
Accumulating evidence supports the importance of leukocyte-endothelial cell adhesion molecule (CAM) ...
<p>The expression of TSLP, IL-25, IL-33, IL-4, IL-5, IL-9 and IL-13 in nasal tissues derived from pa...
Interleukin 10 (IL-10) is a potent anti-inflammatory cytokine. The dysregulation of IL-10 is associa...
Background: Innate immune recognition via Toll-like receptors (TLRs) on barrier cells like epithelia...
BACKGROUND: Allergic inflammation is regulated by the local production and release of several cytoki...
Understanding the function of the nasal vasculature in homeostasis and pathogenesis of common nasal ...
Allergic and infectious rhinitis are prevalent conditions that besides a direct morbidity also cause...
<div><p>Background and Objectives</p><p>Interleukin 10 (IL-10) is a potent anti-inflammatory cytokin...
BACKGROUND: In allergic diseases, like in rhinitis, antigen challenge induces rapid degranulation of...
Background: IL-10 is a major anti-inflammatory cytokine that prevents inflammation-mediated tissue d...
BACKGROUND: Allergic rhinitis (AR) and asthma are characterized by means of a similar inflammatory p...
Although initially described as an immunomodulatory cytokine, interleukin-10 (IL-10) has also been p...
Background: The role of Th2 type cytokines in the persistence of chronic rhinosinusitis, especially ...
BACKGROUND: Allergic rhinitis is an inflammatory disease of the upper airway mucosa that also affect...
Background: Chronic rhinosinusitis (CRS) is characterized by local inflammation of the sinonasal tis...