In this paper, data dealing with the sensitivity of autophagy towards partial ATP depletion in isolated rat hepatocytes are reviewed. Partial reduction of intracellular ATP causes: (1) a decrease of proteolytic flux; (2) a decrease in uptake of cytosolic components into the autophagic-lysosomal compartment; (3) either a decrease or no change in the ratio between volume densities of autophagosomes and lysosomes, depending on whether or not the cytosolic phosphate potential is affected; and (4) impairment of the lysosomal proton pump. It is concluded that the consecutive steps of autophagy all respond to relatively small changes of intracellular ATP concentratio
It was investigated whether rat hepatocytes maintain their plasma membrane specialization (sinusoida...
It was investigated whether rat hepatocytes maintain their plasma membrane specialization (sinusoida...
It was investigated whether rat hepatocytes maintain their plasma membrane specialization (sinusoida...
AbstractThe different turnover rates of rat liver mitochondrial enzymes make autophagy unlikely to b...
In autophagy, a portion of cytoplasm is first segregated into a membrane-bound vacuole which then ac...
Autophagy or autophagocytosis are terms given to a membrane-mediated process in eukaryotic cells in ...
International audienceTwo mechanisms may affect the yield of the oxidative phosphorylation pathway i...
Acid phosphatase activity in isolated rat liver parenchymal cells has been investigated with quantit...
Liver cells of the twenty-one day old rat embryo are isolated by a modified method and autophagy is ...
AbstractRat liver mitochondria contain an ATP-dependent proteolytic system which is localized on the...
AbstractDegradation of the peroxisomal enzymes fatty acyl-CoA oxidase and catalase was studied in he...
Cell death, as estimated by the release of lactate dehydrogenase (LDH), was induced by incubating is...
The contribution of endogenous fluorophores - such as proteins, bound and free NAD(P)H, flavins, vit...
It was investigated whether rat hepatocytes maintain their plasma membrane specialization (sinusoida...
It was investigated whether rat hepatocytes maintain their plasma membrane specialization (sinusoida...
It was investigated whether rat hepatocytes maintain their plasma membrane specialization (sinusoida...
It was investigated whether rat hepatocytes maintain their plasma membrane specialization (sinusoida...
It was investigated whether rat hepatocytes maintain their plasma membrane specialization (sinusoida...
AbstractThe different turnover rates of rat liver mitochondrial enzymes make autophagy unlikely to b...
In autophagy, a portion of cytoplasm is first segregated into a membrane-bound vacuole which then ac...
Autophagy or autophagocytosis are terms given to a membrane-mediated process in eukaryotic cells in ...
International audienceTwo mechanisms may affect the yield of the oxidative phosphorylation pathway i...
Acid phosphatase activity in isolated rat liver parenchymal cells has been investigated with quantit...
Liver cells of the twenty-one day old rat embryo are isolated by a modified method and autophagy is ...
AbstractRat liver mitochondria contain an ATP-dependent proteolytic system which is localized on the...
AbstractDegradation of the peroxisomal enzymes fatty acyl-CoA oxidase and catalase was studied in he...
Cell death, as estimated by the release of lactate dehydrogenase (LDH), was induced by incubating is...
The contribution of endogenous fluorophores - such as proteins, bound and free NAD(P)H, flavins, vit...
It was investigated whether rat hepatocytes maintain their plasma membrane specialization (sinusoida...
It was investigated whether rat hepatocytes maintain their plasma membrane specialization (sinusoida...
It was investigated whether rat hepatocytes maintain their plasma membrane specialization (sinusoida...
It was investigated whether rat hepatocytes maintain their plasma membrane specialization (sinusoida...
It was investigated whether rat hepatocytes maintain their plasma membrane specialization (sinusoida...