The hypothalamo-pituitary-thyroid axis in acromegaly may be altered. Previous studies report diminished serum TSH concentrations in patients with active acromegaly and decreased response to TRH. On the other hand, most patients have normal thyroid hormone concentrations. Our aim was to analyze serum TSH profiles in relation to GH profiles in patients with untreated acromegaly, in order to delineate aberrations in the hypothalamo-pituitary-thyroid system. Twenty-one patients with active acromegaly and matched controls underwent a 24-h, 10-min blood sampling study. GH and TSH data were analyzed with a newly developed automated deconvolution program, approximate entropy, and cosinor regression. Basal (10.4 +/- 2.0 vs. 13.8 +/- 1.4 mU/liter . 2...
Acromegaly is frequently associated with the presence of thyroid disorders, however the exact preval...
TSH secretion, with particular regard to the nocturnal TSH surge, was evaluated in 115 subjects with...
The etiopathogenesis of sporadic central hypothyroidism (CH) involves pituitary and hypothalamic les...
The aim of this study was to evaluate plasma thyrotropin (TSH), prolactin (PRL) and growth hormone (...
Context: Twenty-four-hour TSH secretion profiles in primary hypothyroidism have been analyzed with m...
Objective. The aim of this study was to investigate how the paradoxical response of GH secretion to ...
In healthy subjects, parathyroid hormone (PTH) is secreted in a dual fashion, with low-amplitude and...
OBJECTIVE Since panhypopituitarism in patients with Sheehan's syndrome is due to massive pituitary n...
Purpose. To determine the prevalence, risk factors, and possible mechanisms of structural and endocr...
Acromegaly is frequently associated with the presence of thyroid disorders, however the exact preval...
Seven patients with hyperthyroidism due to a TSH-secreting pituitary macroadenoma have been observed...
Acromegaly is frequently associated with the presence of thyroid disorders, however the exact preval...
Biochemical markers for remission on acromegaly activity are controversial. We studied a subset of t...
Five patients with severe hypothyroidism were studied to determine diurnal variations in serum TSH a...
OBJECTIVE It has previously been shown that patients with postpartum pituitary necrosis (Sheehan's s...
Acromegaly is frequently associated with the presence of thyroid disorders, however the exact preval...
TSH secretion, with particular regard to the nocturnal TSH surge, was evaluated in 115 subjects with...
The etiopathogenesis of sporadic central hypothyroidism (CH) involves pituitary and hypothalamic les...
The aim of this study was to evaluate plasma thyrotropin (TSH), prolactin (PRL) and growth hormone (...
Context: Twenty-four-hour TSH secretion profiles in primary hypothyroidism have been analyzed with m...
Objective. The aim of this study was to investigate how the paradoxical response of GH secretion to ...
In healthy subjects, parathyroid hormone (PTH) is secreted in a dual fashion, with low-amplitude and...
OBJECTIVE Since panhypopituitarism in patients with Sheehan's syndrome is due to massive pituitary n...
Purpose. To determine the prevalence, risk factors, and possible mechanisms of structural and endocr...
Acromegaly is frequently associated with the presence of thyroid disorders, however the exact preval...
Seven patients with hyperthyroidism due to a TSH-secreting pituitary macroadenoma have been observed...
Acromegaly is frequently associated with the presence of thyroid disorders, however the exact preval...
Biochemical markers for remission on acromegaly activity are controversial. We studied a subset of t...
Five patients with severe hypothyroidism were studied to determine diurnal variations in serum TSH a...
OBJECTIVE It has previously been shown that patients with postpartum pituitary necrosis (Sheehan's s...
Acromegaly is frequently associated with the presence of thyroid disorders, however the exact preval...
TSH secretion, with particular regard to the nocturnal TSH surge, was evaluated in 115 subjects with...
The etiopathogenesis of sporadic central hypothyroidism (CH) involves pituitary and hypothalamic les...