Renal impairment in patients with inflammatory bowel disease: association with aminosalicylate therapy?

  • Elseviers, M. M.
  • D'Haens, G.
  • Lerebours, E.
  • Plane, C.
  • Stolear, J. C.
  • Riegler, G.
  • Capasso, G.
  • van Outryve, M.
  • Mishevska-Mukaetova, P.
  • Djuranovic, S.
  • Pelckmans, P.
  • de Broe, M. E.
Publication date
January 2004

Abstract

In recent years, several case reports have been published suggesting an association between the use of 5-aminosalicylic acid (5-ASA) in patients with inflammatory bowel disease (IBD) and the development of chronic tubulo-interstitial nephritis. Apart from lesions associated to 5-ASA treatment, however, it is clear that IBD itself may also induce renal impairment, albeit the frequency is unknown. During 1 year, all IBD patients seen at the outpatient clinic of 27 European centres of gastro-enterology were registered and screened for renal impairment controlling for a possible association with 5-ASA therapy. Patients were questioned about their medical and drug history and their IBD disease activity. Renal screening (calculated creatinine cle...

Extracted data

We use cookies to provide a better user experience.