Fluorescence lifetime of dye molecules is a sensitive reporter on local microenvironment which is generally independent of fluorophores concentration and can be used as a means of discrimination between molecules with spectrally overlapping emission. It is therefore a potentially powerful multiplexed detection modality in biosensing but requires extremely low light level operation typical of biological analyte concentrations, long data acquisition periods and on-chip processing capability to realize these advantages. We report here fluorescence lifetime data obtained using a CMOS-SPAD imager in conjunction with DNA microarrays and TIRF excitation geometry. This enables acquisition of single photon arrival time histograms for a 320 pixel FLI...
Fluorescence lifetime measurement is used in biological research to enhance the contrast of fluoresc...
cDNA-microarrays for expression profiling rely on the assumption that the fluorescence signal is lin...
cDNA-microarrays for expression profiling rely on the assumption that the fluorescence signal is lin...
Fluorescence lifetime of dye molecules is a sensitive reporter on local microenvironment which is ge...
Fluorescence lifetime of dye molecules is a sensitive reporter on local microenvironment which is ge...
Fluorescence lifetime of dye molecules is a sensitive reporter on local microenvironment which is ge...
Optical biosensors are probably the most popular in bioanalysis due to their selectivity and sensiti...
Quantum dot (QD) labeling combined with fluorescence lifetime imaging microscopy is proposed as a po...
Quantum dot (QD) labeling combined with fluorescence lifetime imaging microscopy is proposed as a po...
Quantum dot (QD) labeling combined with fluorescence lifetime imaging microscopy is proposed as a p...
Quantum dot (QD) labeling combined with fluorescence lifetime imaging microscopy is proposed as a p...
Fluorescence-based techniques are amongst the most widely used methods in molecular analysis in life...
Quantum dot (QD) labeling combined with fluorescence lifetime imaging microscopy is proposed as a p...
Quantum dot (QD) labeling combined with fluorescence lifetime imaging microscopy is proposed as a p...
cDNA-microarrays for expression profiling rely on the assumption that the fluorescence signal is lin...
Fluorescence lifetime measurement is used in biological research to enhance the contrast of fluoresc...
cDNA-microarrays for expression profiling rely on the assumption that the fluorescence signal is lin...
cDNA-microarrays for expression profiling rely on the assumption that the fluorescence signal is lin...
Fluorescence lifetime of dye molecules is a sensitive reporter on local microenvironment which is ge...
Fluorescence lifetime of dye molecules is a sensitive reporter on local microenvironment which is ge...
Fluorescence lifetime of dye molecules is a sensitive reporter on local microenvironment which is ge...
Optical biosensors are probably the most popular in bioanalysis due to their selectivity and sensiti...
Quantum dot (QD) labeling combined with fluorescence lifetime imaging microscopy is proposed as a po...
Quantum dot (QD) labeling combined with fluorescence lifetime imaging microscopy is proposed as a po...
Quantum dot (QD) labeling combined with fluorescence lifetime imaging microscopy is proposed as a p...
Quantum dot (QD) labeling combined with fluorescence lifetime imaging microscopy is proposed as a p...
Fluorescence-based techniques are amongst the most widely used methods in molecular analysis in life...
Quantum dot (QD) labeling combined with fluorescence lifetime imaging microscopy is proposed as a p...
Quantum dot (QD) labeling combined with fluorescence lifetime imaging microscopy is proposed as a p...
cDNA-microarrays for expression profiling rely on the assumption that the fluorescence signal is lin...
Fluorescence lifetime measurement is used in biological research to enhance the contrast of fluoresc...
cDNA-microarrays for expression profiling rely on the assumption that the fluorescence signal is lin...
cDNA-microarrays for expression profiling rely on the assumption that the fluorescence signal is lin...