On fundamental implications of systems and synthetic biology

Systems and synthetic biology promise to revolutionize our understanding of biology, blur the boundaries between the living and the engineered in a vital new bioengineering, and transform our daily relationship to the living world. Their emergence thus deserves to be understood in a wider intellectual perspective. Close attention to their relationship to the larger scientific intellectual frameworks within which they function reveals that systems and synthetic biology raise fundamental challenges to scientific orthodoxy, but stand in the vanguard of an emerging new complex dynamical systems paradigm now sweeping across science