Add to ORKGTo maximize the probability of obtaining an antibody peptidase, an efficient assay for the hydrolysis of peptide bonds was developed. Two methods for detecting the uncatalyzed rate of hydrolysis of a peptide bond, without the use of extreme temperature or pH, are described. The uncatalyzed and carboxypeptidase-catalyzed hydrolysis of hippurylphenylalanine was followed under identical conditions by derivatization of the primary-amine product with naphthalenedicarboxaldehyde (NDA). The half-life of this peptide as well as the rate enhancement and catalytic proficiency of carboxypeptidase A were determined. Progress was made in monitoring the hydrolysis of peptidyl-prolyl bonds by derivatization of the secondary-amine product with 4-(dimethyla...
The use of enzymes for protein labeling promises many advantages over the traditional chemical metho...
An approximate molecular orbital method is used to study the catalytic activity of carboxypeptidase ...
A new approach for producing catalytic antiidiotypic antibody was developed. A monoclonal anti-idiot...
The exo-(1-amino-2-hydroxy)bicyclo (2.2,1) heptane-7-carboxylic acid derivatives I and II have been ...
Antibodies are immunoglobulins that bind to stable ground-state molecules and recognise their respec...
Antibodies are immunoglobulins that bind to stable ground-state molecules and recognise their respec...
Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1999.Vita.Includes biblio...
Using an enzyme of known specificity the hydrolysis of protein was carried out in a controlled manne...
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Chemical Engineering, February ...
This thesis describes the development and study of catalytic antibodies capable of peptide bond form...
The piperidine-based hapten 1 generates monoclonal antibodies that catalyze the hydrolysis of substr...
Amidase antibody 312d6, obtained against the sulfonamide hapten 4a that mimics the transition state ...
The piperidine-based hapten 1 generates monoclonal antibodies that catalyze the hydrolysis of substr...
The use of enzymes for protein labeling promises many advantages over the traditional chemical metho...
The use of enzymes for protein labeling promises many advantages over the traditional chemical metho...
The use of enzymes for protein labeling promises many advantages over the traditional chemical metho...
An approximate molecular orbital method is used to study the catalytic activity of carboxypeptidase ...
A new approach for producing catalytic antiidiotypic antibody was developed. A monoclonal anti-idiot...
The exo-(1-amino-2-hydroxy)bicyclo (2.2,1) heptane-7-carboxylic acid derivatives I and II have been ...
Antibodies are immunoglobulins that bind to stable ground-state molecules and recognise their respec...
Antibodies are immunoglobulins that bind to stable ground-state molecules and recognise their respec...
Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1999.Vita.Includes biblio...
Using an enzyme of known specificity the hydrolysis of protein was carried out in a controlled manne...
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Chemical Engineering, February ...
This thesis describes the development and study of catalytic antibodies capable of peptide bond form...
The piperidine-based hapten 1 generates monoclonal antibodies that catalyze the hydrolysis of substr...
Amidase antibody 312d6, obtained against the sulfonamide hapten 4a that mimics the transition state ...
The piperidine-based hapten 1 generates monoclonal antibodies that catalyze the hydrolysis of substr...
The use of enzymes for protein labeling promises many advantages over the traditional chemical metho...
The use of enzymes for protein labeling promises many advantages over the traditional chemical metho...
The use of enzymes for protein labeling promises many advantages over the traditional chemical metho...
An approximate molecular orbital method is used to study the catalytic activity of carboxypeptidase ...
A new approach for producing catalytic antiidiotypic antibody was developed. A monoclonal anti-idiot...