Effects of cognitive, motor, and sensory disabilities on survival in cerebral palsy

Background: Cerebral palsy presents with a range of severity of cognitive, motor, and sensory disabilities, which might affect survival. Aims: To quantify the effects of motor, cognitive, and sensory disabilities, year of birth, birth weight, and gestational age on survival in cerebral palsy. Methods: A cohort of children with cerebral palsy born between 1966 and 1989 to mothers resident in a defined geographical region was subdivided into early impairment (EICP: cerebral insult prenatally or within 28 days of birth) or late impairment (LICP: insult at least 28 days after birth). Deaths are notified by the National Health Service Central Register, Birth and disability details were obtained from clinical records. Survival analyses were carried out. Results: Severe motor disability was associated with a 30 year survival of 42% and severe cognitive disability with a 30 year survival of 62%. Severe visual disability was associated with a 30 year survival of 38%, but the association of survival with hearing disability was weak. EICP had better survival than LICP but the difference was not significant after allowing for severity of functional disabilities. Normal birth weight infants (greater than or equal to2500 9) showed no birth cohort effect, but the 10 year survival of low birth weight (