noHuman saphenous vein endothelial cells (HSVECs) derived from primary cultures of adult human veins constitute an excellent in vitro model for studying human endothelial metabolism. In this study we report the14C-labelled prostanoid profile of HSVECs under resting and stimulated conditions and the effect of the n-3 polyunsaturated fatty acids eicosapentaenoic acid and docosahexaenoic acid on them. Results indicate that HSVECs while under resting conditions produce mainly prostaglandin F2 ¿(PGF2 ¿). After stimulation with calcium ionophore A23187, the cells were found to synthesise PGI2, PGE2and PGF2¿as major products and thromboxane B2and PGD2as minor products. Production of14C-labelled hydroxyeicosatetraenoic acids was not detected. Eicos...
-binding proteins, plays a pivotal role in vascular biology. Small amounts of this protein and S100A...
<p>Previous studies show that inhibition of delta-5 desaturase and delta-6 causes a<br>decrease in p...
Eicosanoids are the major metabolites of fatty acids and they are correlated with many kinds of dise...
153 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1983.An endothelial cell culture s...
[[abstract]]Eicosanoids comprise a large array of small-molecular-weight compounds that are synthesi...
Although the correlation between polyunsaturated fatty acids (PUFA) and the production of pro- and a...
Although the correlation between polyunsaturated fatty acids (PUFA) and the production of pro- and a...
Although the correlation between polyunsaturated fatty acids (PUFA) and the production of pro- and a...
Summaryω-3 fatty acids, such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have ben...
NoThe effects of a conjugated linoleic acid (CLA) mixture of single isomers (50:50, w/w, cis9,trans1...
Background: Cardiovascular effects of omega-3 polyunsaturated fatty acids including eicosapentaenoic...
In this study, formation of arachidonic acid-derived prostanoids was investi-gated in saphenous vein...
Human umbilical vessels are not innervated, and hence regulation of tone in these vessels must come ...
Background: Different series prostaglandins (PGs) and leukotrienes (LTs) are synthesized from differ...
Introduction: Prostaglandins (PG) and leukotrienes (LT) are usually formed from arachidonic acid (e....
-binding proteins, plays a pivotal role in vascular biology. Small amounts of this protein and S100A...
<p>Previous studies show that inhibition of delta-5 desaturase and delta-6 causes a<br>decrease in p...
Eicosanoids are the major metabolites of fatty acids and they are correlated with many kinds of dise...
153 p.Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1983.An endothelial cell culture s...
[[abstract]]Eicosanoids comprise a large array of small-molecular-weight compounds that are synthesi...
Although the correlation between polyunsaturated fatty acids (PUFA) and the production of pro- and a...
Although the correlation between polyunsaturated fatty acids (PUFA) and the production of pro- and a...
Although the correlation between polyunsaturated fatty acids (PUFA) and the production of pro- and a...
Summaryω-3 fatty acids, such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have ben...
NoThe effects of a conjugated linoleic acid (CLA) mixture of single isomers (50:50, w/w, cis9,trans1...
Background: Cardiovascular effects of omega-3 polyunsaturated fatty acids including eicosapentaenoic...
In this study, formation of arachidonic acid-derived prostanoids was investi-gated in saphenous vein...
Human umbilical vessels are not innervated, and hence regulation of tone in these vessels must come ...
Background: Different series prostaglandins (PGs) and leukotrienes (LTs) are synthesized from differ...
Introduction: Prostaglandins (PG) and leukotrienes (LT) are usually formed from arachidonic acid (e....
-binding proteins, plays a pivotal role in vascular biology. Small amounts of this protein and S100A...
<p>Previous studies show that inhibition of delta-5 desaturase and delta-6 causes a<br>decrease in p...
Eicosanoids are the major metabolites of fatty acids and they are correlated with many kinds of dise...