Copolymères amphiphiles biodégradables pour la vectorisation

The development of controlled drug delivery systems is today a topic of an intense research activity. In this field, biocompatible and (bio)degradable polymers are particularly studied. The production of nanosized particles (polymer micelles, nanoparticles,...) generally requires the elaboration of functional amphiphilic copolymers able to stabilize efficiently these colloidal dispersions. Various strategies to synthesize such copolymers keeping their (bio)degradability are described here. The complexity of these amphiphilic materials will be gradually increased in parallel to the improvement of the nanocarriers properties