Add to ORKGGalectin-3 is a pleiotropic carbohydrate-binding protein involved in a variety of normal and pathological biological processes. Its carbohydrate-binding properties constitute the basis for cell-cell and cell-matrix interactions and cancer progression. Modulation of galectin-3 expression in cancer cells has indeed been reported. These observations lead to the recognition of galectin-3 as a diagnostic/prognostic marker for specific cancer types, such as thyroid and prostate. This review discusses the expression and cellular localization of galectin-3 in cancer cells, as well as its numerous functions in cancer cell biology, including cell-cell adhesion, cell-matrix interactions, growth regulation, apoptosis, angiogenesis and mRNA splicing
Galectins (S-type lectins) are an evolutionarily-conserved family of lectin molecules, which can be ...
The cell surface is covered by different oligosaccharides, which are anchored in the plasmatic membr...
Galectin-3, a member of the beta-galactoside-binding lectin family, is involved in a variety of biol...
peer reviewedGalectin-3 is a pleiotropic carbohydrate-binding protein involved in a variety of norma...
Galectins constitute an evolutionary conserved family that binds to β-galactosides. There is growing...
Interactions between two cells or between cell and extracellular matrix mediated by protein–carbohyd...
The galectins are a family of proteins that are distributed widely in all living organisms. All of t...
Galectin-3 is a carbohydrate-binding protein and regulates diverse functions, including cell prolife...
Galectins are a group of proteins that bind β-galactosides through evolutionarily conserved sequence...
BACKGROUND. Galectin-3 is a carbohydrate-binding protein whose level of expression has been shown to...
peer reviewedGalectin-3, a multifunctional lectin, is involved during cancer progression. Previous o...
Abstract Background Galectin-3 as a β-galactoside-binding protein, has been found to be involved in ...
BACKGROUND Galectin-3 is a carbohydrate-binding protein whose level of expression has been shown to...
BACKGROUND & AIMS: Galectins are beta-galactoside-binding proteins possibly involved in tumor progre...
Galectin-3, a member of the beta-galactoside-binding lectin family, is involved in several biologica...
Galectins (S-type lectins) are an evolutionarily-conserved family of lectin molecules, which can be ...
The cell surface is covered by different oligosaccharides, which are anchored in the plasmatic membr...
Galectin-3, a member of the beta-galactoside-binding lectin family, is involved in a variety of biol...
peer reviewedGalectin-3 is a pleiotropic carbohydrate-binding protein involved in a variety of norma...
Galectins constitute an evolutionary conserved family that binds to β-galactosides. There is growing...
Interactions between two cells or between cell and extracellular matrix mediated by protein–carbohyd...
The galectins are a family of proteins that are distributed widely in all living organisms. All of t...
Galectin-3 is a carbohydrate-binding protein and regulates diverse functions, including cell prolife...
Galectins are a group of proteins that bind β-galactosides through evolutionarily conserved sequence...
BACKGROUND. Galectin-3 is a carbohydrate-binding protein whose level of expression has been shown to...
peer reviewedGalectin-3, a multifunctional lectin, is involved during cancer progression. Previous o...
Abstract Background Galectin-3 as a β-galactoside-binding protein, has been found to be involved in ...
BACKGROUND Galectin-3 is a carbohydrate-binding protein whose level of expression has been shown to...
BACKGROUND & AIMS: Galectins are beta-galactoside-binding proteins possibly involved in tumor progre...
Galectin-3, a member of the beta-galactoside-binding lectin family, is involved in several biologica...
Galectins (S-type lectins) are an evolutionarily-conserved family of lectin molecules, which can be ...
The cell surface is covered by different oligosaccharides, which are anchored in the plasmatic membr...
Galectin-3, a member of the beta-galactoside-binding lectin family, is involved in a variety of biol...