People with chronic kidney disease (CKD) of stages 3-4 (creatinine clearance <50 ml/min) represent 25-30% of type 2 diabetic patients, but the problem is often underrecognized or neglected in clinical practice. However, most of oral antidiabetic agents have limitations in case of renal impairment, either because they require a dose adjustment, or because they are contra-indicated for safety reasons. It is the case for metformin (risk of lactic acidosis) and for most sulfonylureas (risk of hypoglycaemia). New antidiabetic agents are better tolerated in case of CKD. However, the daily dose of dipeptidyl peptidase-4 inhibitors should be adjusted (except for linagliptin). Concerning new inhibitors of renal SGLT2 cotransporters, they have a redu...
peer reviewedSodium-glucose cotransporter type 2 inhibitors (iSGLT2 or gliflozins) exert their antid...
Inhibitors of sodium-glucose cotransporters type 2 (SGLT2) are proposed as a novel approach for the ...
peer reviewedChronic kidney disease is a prevalent complication of type 2 diabetes mellitus (T2DM). ...
Worldwide, an estimated 200 million people have chronic kidney disease (CKD), the most common causes...
Worldwide, an estimated 200 million people have chronic kidney disease (CKD), the most common causes...
Worldwide, an estimated 200 million people have chronic kidney disease (CKD), whose most common caus...
Chronic kidney disease (CKD) represents a challenge in the treatment of type 2 diabetic patients. Re...
Patients with diabetes are at risk of early renal function decline. Therefore, kidney function needs...
Introduction: People with chronic kidney disease (CKD) of stages 3 - 5 (creatinine clearance < 60 ml...
Diabetes is the most common cause of kidney failure worldwide. Patients with diabetes and chronic ki...
The achievement of a good glycaemic control is one of the cornerstones for preventing and delaying p...
The prevalence of chronic kidney disease (CKD) of stages 3-5 (glomerular filtration rate [GFR] <60 m...
Diabetic kidney disease is among the most frequent complications of diabetes, with approximately 50%...
The management of patients with type 2 diabetes and chronic kidney disease (CKD) encompasses lifesty...
The achievement of a good glycaemic control is one of the cornerstones for preventing and delaying p...
peer reviewedSodium-glucose cotransporter type 2 inhibitors (iSGLT2 or gliflozins) exert their antid...
Inhibitors of sodium-glucose cotransporters type 2 (SGLT2) are proposed as a novel approach for the ...
peer reviewedChronic kidney disease is a prevalent complication of type 2 diabetes mellitus (T2DM). ...
Worldwide, an estimated 200 million people have chronic kidney disease (CKD), the most common causes...
Worldwide, an estimated 200 million people have chronic kidney disease (CKD), the most common causes...
Worldwide, an estimated 200 million people have chronic kidney disease (CKD), whose most common caus...
Chronic kidney disease (CKD) represents a challenge in the treatment of type 2 diabetic patients. Re...
Patients with diabetes are at risk of early renal function decline. Therefore, kidney function needs...
Introduction: People with chronic kidney disease (CKD) of stages 3 - 5 (creatinine clearance < 60 ml...
Diabetes is the most common cause of kidney failure worldwide. Patients with diabetes and chronic ki...
The achievement of a good glycaemic control is one of the cornerstones for preventing and delaying p...
The prevalence of chronic kidney disease (CKD) of stages 3-5 (glomerular filtration rate [GFR] <60 m...
Diabetic kidney disease is among the most frequent complications of diabetes, with approximately 50%...
The management of patients with type 2 diabetes and chronic kidney disease (CKD) encompasses lifesty...
The achievement of a good glycaemic control is one of the cornerstones for preventing and delaying p...
peer reviewedSodium-glucose cotransporter type 2 inhibitors (iSGLT2 or gliflozins) exert their antid...
Inhibitors of sodium-glucose cotransporters type 2 (SGLT2) are proposed as a novel approach for the ...
peer reviewedChronic kidney disease is a prevalent complication of type 2 diabetes mellitus (T2DM). ...