peer reviewedBy microscopical observation and using an original morphometric method, we analyzed on histological sections the rate of lung colony formation after the intravenous injection into the mouse of B16 melanoma cells previously cultivated in vitro as aggregates. After the injection of B16 pure spheroids, superficial lung colonies were more numerous than internal lung colonies. After the injection of mixed spheroids (B16 + 3T3 fibroblasts), the size of colony sections was increased. Addition of laminin to pure or mixed spheroids decreased the size of colony sections but increased the number of internal lung colonies
<p>Melanoma bearing mice were injected i.t. with 50 μl of BAM derivatives of agonists (0.2 mM lamina...
Several variant cell lines that are deficient in surface laminin have been isolated from heterogeneo...
Monoclonal antibodies reacting exclusively with laminin of human origin and a polyclonal antibody re...
A recently described personal method based on image analysis of histological sections was used in or...
Multicellular spheroids which promote cell-cell and cell-matrix interactions were prepared in cultur...
The interactions between invasive malignant cells and normal fibroblastic cells were studied in a ce...
Multicellular spheroids composed of mouse B16 melanoma cells have been prepared in non agitated cult...
peer reviewedA parental line of mouse B16 melanoma cells (B16) and two derived cloned lines, either ...
Melanoma is a tumor where virulence is conferred on transition from flat (radial) to three-dimension...
AbstractLaminin is a major component of basement membranes. We previously reported that the globular...
A reconstituted basement membrane (matrigel) and/or fibroblasts promote the growth of human breast t...
<p>To the mixture of melanoma B16-F10 cells and macrophage cell line PMJ2R laminarin-BAM (A) or free...
We recently found that polyclonal antibodies to laminin, a basement membrane-related glycoprotein, i...
Laminin has been shown to promote the malignant phenotype and the level of the 32/67 Kd laminin rece...
The pattern of deposition and the role of laminin, a major glycoprotein constituent of basement memb...
<p>Melanoma bearing mice were injected i.t. with 50 μl of BAM derivatives of agonists (0.2 mM lamina...
Several variant cell lines that are deficient in surface laminin have been isolated from heterogeneo...
Monoclonal antibodies reacting exclusively with laminin of human origin and a polyclonal antibody re...
A recently described personal method based on image analysis of histological sections was used in or...
Multicellular spheroids which promote cell-cell and cell-matrix interactions were prepared in cultur...
The interactions between invasive malignant cells and normal fibroblastic cells were studied in a ce...
Multicellular spheroids composed of mouse B16 melanoma cells have been prepared in non agitated cult...
peer reviewedA parental line of mouse B16 melanoma cells (B16) and two derived cloned lines, either ...
Melanoma is a tumor where virulence is conferred on transition from flat (radial) to three-dimension...
AbstractLaminin is a major component of basement membranes. We previously reported that the globular...
A reconstituted basement membrane (matrigel) and/or fibroblasts promote the growth of human breast t...
<p>To the mixture of melanoma B16-F10 cells and macrophage cell line PMJ2R laminarin-BAM (A) or free...
We recently found that polyclonal antibodies to laminin, a basement membrane-related glycoprotein, i...
Laminin has been shown to promote the malignant phenotype and the level of the 32/67 Kd laminin rece...
The pattern of deposition and the role of laminin, a major glycoprotein constituent of basement memb...
<p>Melanoma bearing mice were injected i.t. with 50 μl of BAM derivatives of agonists (0.2 mM lamina...
Several variant cell lines that are deficient in surface laminin have been isolated from heterogeneo...
Monoclonal antibodies reacting exclusively with laminin of human origin and a polyclonal antibody re...
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