Add to ORKGMulticellular spheroids which promote cell-cell and cell-matrix interactions were prepared in culture with mouse B16 melanoma cells (pigmented or non pigmented) alone or mixed with mouse 3T3 fibroblasts. Their volume and proliferation or necrosis rate were evaluated. As measured by dot blot immunoassay, laminin was mainly produced by fibroblasts rather than by melanoma cells. High levels of laminin B1 chain mRNA were detected only in spheroids composed of 3T3 fibroblasts. The levels of 67 kD laminin binding protein mRNA were high in all cell populations studied here
A reconstituted basement membrane (matrigel) and/or fibroblasts promote the growth of human breast t...
We are studying the ability of colorectal carcinomas, which vary in degree of differentiation, to as...
Laminins are cell adhesion molecules that comprise a family of glycoproteins found predominantly in ...
We have cultured normal fibroblasts, fibrosarcoma HT1080 cells and breast adenocarcinoma MCF-7 cells...
Monoclonal antibodies reacting exclusively with laminin of human origin and a polyclonal antibody re...
The possible mitogenic activity of laminin (LN) on normal and neoplastic cells of the melanocyte Lin...
peer reviewedBy microscopical observation and using an original morphometric method, we analyzed on ...
Multicellular spheroids composed of mouse B16 melanoma cells have been prepared in non agitated cult...
Interaction between the 67 kilodalton metastasis-associated laminin receptor and laminin. Normal and...
Among the various known laminin binding proteins, the 67 kD high affinity laminin receptor (LR) is i...
Several variant cell lines that are deficient in surface laminin have been isolated from heterogeneo...
peer reviewedLaminin, a major glycoprotein of basement membrane has been found to play significant r...
The interactions between invasive malignant cells and normal fibroblastic cells were studied in a ce...
Laminin has been shown to promote the malignant phenotype and the level of the 32/67 Kd laminin rece...
peer reviewedInteractions between cancer cells and laminin, a major component of basement membranes,...
A reconstituted basement membrane (matrigel) and/or fibroblasts promote the growth of human breast t...
We are studying the ability of colorectal carcinomas, which vary in degree of differentiation, to as...
Laminins are cell adhesion molecules that comprise a family of glycoproteins found predominantly in ...
We have cultured normal fibroblasts, fibrosarcoma HT1080 cells and breast adenocarcinoma MCF-7 cells...
Monoclonal antibodies reacting exclusively with laminin of human origin and a polyclonal antibody re...
The possible mitogenic activity of laminin (LN) on normal and neoplastic cells of the melanocyte Lin...
peer reviewedBy microscopical observation and using an original morphometric method, we analyzed on ...
Multicellular spheroids composed of mouse B16 melanoma cells have been prepared in non agitated cult...
Interaction between the 67 kilodalton metastasis-associated laminin receptor and laminin. Normal and...
Among the various known laminin binding proteins, the 67 kD high affinity laminin receptor (LR) is i...
Several variant cell lines that are deficient in surface laminin have been isolated from heterogeneo...
peer reviewedLaminin, a major glycoprotein of basement membrane has been found to play significant r...
The interactions between invasive malignant cells and normal fibroblastic cells were studied in a ce...
Laminin has been shown to promote the malignant phenotype and the level of the 32/67 Kd laminin rece...
peer reviewedInteractions between cancer cells and laminin, a major component of basement membranes,...
A reconstituted basement membrane (matrigel) and/or fibroblasts promote the growth of human breast t...
We are studying the ability of colorectal carcinomas, which vary in degree of differentiation, to as...
Laminins are cell adhesion molecules that comprise a family of glycoproteins found predominantly in ...